CD5

Mantle cell lymphoma stained with CD5 antibody

CD5 is a T-cell associated marker that is also expressed by two B-cell neoplasms, lymphocytic leukemia and mantle cell lymphoma. CD5 antigen is expressed in 95% of thymocytes and 72% of peripheral blood lymphocytes. It has been shown to react with thymic carcinomas but rarely in thyomas. It has also been observed in a subset of intravascular large B-cell lymphomas and marks some anaplastic large cell lymphomas. CD5 has proven very useful in marking mantle cell lymphoma when used in tandem with Cyclin D1, CD10 and CD23. CD5 is postive for mantle cell lymphoma.

Specifications  
Intended Use
Source
Species Reactivity ,
Clone
Isotype
Antigen
Cellular Localization
Positive Control ,
Normal Tissue
Abnormal Tissue
Ordering Information Catalog Number Volume
Concentrate CRM 328 AK, BK
Predilute PRM 328 AA
intelliPATH™ IP 328 G10
VP Echelon Use Predilute
A / AK = 0.1 ml B / BK = 0.5 ml C / CK = 1.0 ml G5 = 5.0 ml AA = 6.0 ml H / G25 = 25 ml L = 100 ml