PGP9.5
Protein Gene Product 9.5 (PGP 9.5) is also known as ubiquitin C-terminal hydrolase 1 (UCHL-1). Expression of PGP9.5 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. The PGP9.5 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson’s disease susceptibility. It is estimated that PGP9.5 comprises 1-2 % of total soluble proteins in the brain. Immunohistochemistry of routinely processed neuronal tissues has identified central and peripheral nerve fibers of all types. PGP9.5 has been identified in renal tubule, spermatogonia, Leydig cells of the testis and in pregnant and non pregnant corpus luteum.
| Ordering Information |
Catalog Number |
Volume |
| Concentrate |
CM 329 |
AK |
| Predilute |
N/A |
N/A |
| intelliPATH™ |
N/A |
N/A |
| VP Echelon |
N/A |
N/A |
| A / AK = 0.1 ml |
B / BK = 0.5 ml |
C / CK = 1.0 ml |
G5 = 5.0 ml |
AA = 6.0 ml |
H / G25 = 25 ml |
L = 100 ml |
