Myogenin

Rhabdomyosarcoma stained with Myogenin antibody

Myogenin is a member of a family of myogenic genes that also includes MyoD. These genes encode a set of transcription factors that are essential for muscle development. Expression of myogenin is restricted to cells of skeletal muscle origin. Clone MG007 has been shown to label human myogenin and label neonatal mouse, rat and cat tissues. Staining has also been found in myoblasts from human fetal limbs. No reactivity was found in adult skeletal muscle. Myogenin has been observed to stain the vast majority of rhabdomyosarcomas and Wilm’s tumors. No activity was observed in Ewing’s sarcoma/peripheral primitive neuroectodermal tumor, or in neuroblastomas.

Specifications  
Intended Use
Source
Species Reactivity , ,
Clone
Isotype ,
Antigen
Cellular Localization
Positive Control
Normal Tissue
Abnormal Tissue
Ordering Information Catalog Number Volume
Concentrate CM 115 A, C
Predilute PM 115 AA
intelliPATH™ IP 115 G10
VP Echelon N/A N/A
A / AK = 0.1 ml B / BK = 0.5 ml C / CK = 1.0 ml G5 = 5.0 ml AA = 6.0 ml H / G25 = 25 ml L = 100 ml
Data Sheets
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