CD24
CD24 (30-70kDa molecular weight) is a two chain glycosylphosphatidylinositol (GPI) –anchored glycoprotein. It is a mucin-like adhesion molecule. CD24 functionally enhances the metastatic potential of malignant-cells, as it has been also identified as a ligand of P-selectin, an adhesion receptor on activated endothelial cells and platelets. Research has shown CD24 expression as a potentially significant parameter for a wide variety of human cancer diagnosis and for patient prognosis. Elevated CD24 membranous expression and, in particular, cytoplasmic staining seem to predict malignant transformation. Recent studies have shown CD24 as a prognostic marker for breast cancer and more specifically for tamoxifen-resistant breast cancer cases. Further studies have shown a subpopulation (CD44+/CD24-) of breast cancer cells reported to have stem/progenitor cell properties.
| Ordering Information |
Catalog Number |
Volume |
| Concentrate |
CM 323 |
A, B |
| Predilute |
N/A |
N/A |
| intelliPATH™ |
N/A |
N/A |
| VP Echelon |
N/A |
N/A |
| A / AK = 0.1 ml |
B / BK = 0.5 ml |
C / CK = 1.0 ml |
G5 = 5.0 ml |
AA = 6.0 ml |
H / G25 = 25 ml |
L = 100 ml |
