ALDH1a1 Rabbit Monoclonal
Aldh1a1 (Aldehyde dehydrogenase 1). The Aldh1a1 gene encodes the major cytosolic Aldh1a1 existing in the liver and other tissues. The genetic deficiency of this isozyme has been found at a low frequency (< 10%) in both Caucasians and Asians. Studies have shown that Aldh1a1 in normal and cancer human mammary epithelial cells with increased aldehyde dehydrogenase activity have stem/progenitor like properties. In a series of 577 breast carcinomas, expression of Aldh1a1 detected by immunostaining correlated with poor prognosis. These findings offer an important new tool for the study of normal and malignant breast stem cells and facilitate the clinical application of stem cell concepts.
| Ordering Information |
Catalog Number |
Volume |
| Concentrate |
CME 351 |
AK, CK |
| Predilute |
N/A |
N/A |
| intelliPATH™ |
N/A |
N/A |
| VP Echelon |
N/A |
N/A |
| A / AK = 0.1 ml |
B / BK = 0.5 ml |
C / CK = 1.0 ml |
G5 = 5.0 ml |
AA = 6.0 ml |
H / G25 = 25 ml |
L = 100 ml |
