HER2/neu [IHC042]

Product Description

HER-2/Neu (also known as ERBB2 or HER2) is a member of the human epidermal growth factor receptor, family of tyrosine kinases, involved in critical signaling pathways that control cell proliferation and survival.¹ HER2/Neu protein overexpression is associated with breast, ovary, endometrium, cervix as well as lung, esophageal, gastric, and bladder cancers.2 HER-2/Neu is an important target for anticancer treatment strategies.²

Specifications

1. Eswarachary V, Mohammed IG, Jayanna PK, et al. HER2/neu Testing In 432 Consecutive Breast Cancer Cases using FISH and IHC – A Comparative Study. J Clin Diagn Res. 2017;11(4):EC01-EC05.
2. Albagoush SA, Limaiem F. HER2. 2020 Nov 3. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan–. PMID: 30725819.
3. Center for Disease Control Manual. Guide: Safety Management, NO. CDC- 22, Atlanta, GA. April 30, 1976 “Decontamination of Laboratory Sink Drains to Remove Azide Salts.”
4. Clinical and Laboratory Standards Institute (CLSI). Protection of Laboratory Workers from Occupationally Acquired Infections; Approved Guideline-Fourth Edition CLSI document M29-A4 Wayne, PA 2014.