Cytokeratin 17 – CK17

Product Description

CK17 antibody reacts with a 40kDa polypeptide and CK17 is a type I keratin. Studies have shown that it is indicated as an excellent marker for the identification of squamous cell carcinomas in various tissues including the cervix, lung, and oral cavity.¹⁸ CK17 may be helpful to aid in distinguishing myoepithelial cells from luminal epithelium of various glands such as mammary, sweat and salivary. According to studies, expression of CK17 in breast cancer has been associated with a worse prognosis, high tumor grade and positive axillary lymph nodes.^15-18

Specifications

1. van de Rijn M, et al. Am J Pathol. 2002 Dec; 161(6):1991-6.
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5. Lerma E, Barnadas A, Prat J. Appl Immunohistochem Mol Morphol. 2009 Dec; 17(6):483-94.
6. Liu ZB, et al. Tumori. 2009 Jan-Feb; 95(1):53-62.