This rabbit monoclonal antibody recognizes a protein of 36 kDa, identified as Cyclin D1 antibody rabbit (also known as Bcl-1 or PRAD-1). Cyclin D1 antibody rabbit is a regulatory subunit of certain protein kinases thought to advance the G1 phase of the cell cycle. Cyclin D1, when used in tandem with CD5, CD10 and CD23, is a reliable immunohistochemical marker for the mantle cell lymphoma. Studies have shown that Cyclin D1 is a clinical informative marker for invasive breast cancer. Due to the superior technology in the development of this antibody, its binding capacity exceeds mouse monoclonal antibodies and is virtually background free.