CD56 antibody (neural cell adhesion molecule, a natural killer cell marker) is part of a family of cell surface glycoproteins that plays a role in embryogenesis and contact-mediated interactions between neural cells. Studies have shown CD56 to be expressed in a variety of normal and abnormal tissues including skin, small cell carcinoma, neuroblastoma, neurons, astrocytes, Schwann cells, natural killer (NK) cells and a subset of activated T-cell lymphomas.
1. Gattenlöhner S, et al. Am J Pathol. 2009 Apr; 174(4):1160-71.
2. Marafioti T, et al. Blood. 2008 Apr; 111(7):3778-92.
3. Chang CC, et al. Am J Clin Pathol 2000 Nov; 114(5):807-11.
4. Savoia P, et al. Br J Dermatol 1997 Dec; 137(6):966-71.
5. Natkunam Y, et al. J Cutan Pathol 2000 Sep; 27(8):392-9.