The Desmin [D33] antibody is a mouse monoclonal antibody that recognizes a 53 kDa intermediate filament protein identified as desmin. Studies have shown this monoclonal antibody is highly specific to desmin and shows no cross-reaction with other intermediate filament proteins.17 Antibody to desmin reacts with striated (skeletal and cardiac) as well as smooth muscle cells. […]
What Tissues Are You Working With?
Biocare Medical takes great pride in our promise of “Fighting Cancer, One Slide at a Time.” Our focus in the fight against cancer is realized through our high-quality immunohistochemistry (IHC) and in situ hybridization (ISH) reagents and instrumentation. Specifically, our sensitive and specific antibodies, molecular probes, and detection chemistries support early and accurate classification of […]
The Biocare Vimentin antibody detects a 57–60 kDa intermediate filament protein identified as vimentin. This antibody shows no cross-reactivity with closely related intermediate filament proteins, such as desmin or GFAP.15 Vimentin is the principal intermediate filament protein in mesenchymal cells and is useful in the differential diagnosis of undifferentiated neoplasms, including melanoma and sarcoma.16,17 It […]
Neurofilaments antibody are the intermediate filaments of neurons. Studies have shown this antibody stains the 70 kDa and 200 kDa polypeptides of neurofilaments. It stains neurons in tissue sections of brain and other tissues. It does not cross-react with other intermediate filaments such as GFAP, keratin, vimentin and desmin and does not react with small […]
The Muscle Specific Actin antibody [HHF35] recognizes muscle specific alpha and gamma actin isomers. It does not react with non-muscle actin. Studies have shown that it recognizes the alpha actin from cardiac, skeletal and smooth muscle sources. It does not react with beta or non-smooth muscle gamma actin isomers. The antibody labels leiomyoma, leiomyosarcoma, angiomyolipoma […]
