Thyroid Stimulating Hormone (TSH)

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Thyroid Stimulating Hormone antibody (also known as TSH or thyrotropin) is a peptide hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland, which regulates the endocrine function of the thyroid gland. Thyroid Stimulating Hormone antibody may be a useful marker in the classification of pituitary adenomas and can aid in the differential identification of primary and metastatic tumors of the pituitary. TSH secreting pituitary adenomas is a very rare cause of hyperthyroidism.

Intended Use

IVD

Species Reactivity

Human

Source

Mouse Monoclonal

Clone

TSH01 + TSH02

Isotype

IgG1 /kappa

Antigen

TSH-β

Localization

Cytoplasmic

Positive Control

Anterior pituitary

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Regulatory Notice: Biocare’s IVD-labeled products comply with US-FDA and European IVDD regulation. Other regions may have additional requirements for such labeling, please contact your local distributor.

1. Jha S, Kumar S. TSH secreting pituitary adenoma. J Assoc Physicians India. 2009; 57:537-9.
2. Foppiani L, et al. TSH-secreting adenoma: rare pituitary tumors with multifaceted clinical and biological features. J Endocrinol Invest. 2007; 30(7): 603-9.
3. Ness-Abramof R, et al. TSH-secreting pituitary adenomas: follow-up of 11 cases and review of the literature. Pituitary. 2007; 10(3): 307-10.
4. Center for Disease Control Manual. Guide: Safety Management, NO. CDC-22, Atlanta, GA. April 30, 1976 “Decontamination of Laboratory Sink Drains to Remove Azide Salts.”
5. Clinical and Laboratory Standards Institute (CLSI). Protection of Laboratory workers from occupationally Acquired Infections; Approved guideline-Third Edition CLSI document M29-A3 Wayne, PA 2005.

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