PGP9.5 [UCHL1/4556R]

Product Description

Protein gene product 9.5 (PGP 9.5), also known as ubiquitin carboxyl-terminal hydrolase-1 (UCH-L1), is a 27-kDa protein originally isolated from whole brain extracts.¹⁵ The protein is highly conserved and localized in neurons and neuroendocrine cells, forming an estimated 5-10% of cytoplasmic protein.¹⁶ The detection of fine nerves in peripheral tissues using PGP 9.5 antibodies is a widespread IHC application.¹⁶

Specifications

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16. Day IN, Thompson RJ. UCHL1 (PGP 9.5): neuronal biomarker and ubiquitin system protein. Prog Neurobiol. 2010 Mar;90(3):327-62.