High molecular weight cytokeratins are expressed in a variety of normal and neoplastic epithelial tissues (1). In prostate, CK HMW [34βE12] has been shown to be a useful marker of basal cells of normal glands and prostatic intraepithelial neoplasia (PIN), a precursor lesion to prostatic adenocarcinoma; whereas invasive prostatic adenocarcinoma typically lacks a basal cell […]
High molecular weight cytokeratins are expressed in a variety of normal and neoplastic epithelial tissues (1). In prostate, CK HMW [34βE12] has been shown to be a useful marker of basal cells of normal glands and prostatic intraepithelial neoplasia (PIN), a precursor lesion to prostatic adenocarcinoma; whereas invasive prostatic adenocarcinoma typically lacks a basal cell […]
Napsin A (P), 2X is being discontinued. We will continue to offer these products until 06/30/16 or until current inventory is depleted, whichever occurs first. Biocare does offer Napsin A or Napsin A (RM), catalog numbers PP434 or ACI3043, API3043 as a substitute. Napsin A antibody is a pepsin-like aspartic proteinase. It is expressed in […]
p63 has been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with reported sensitivities of 80-100% (1-6). Specificity for lung SqCC, versus lung adenocarcinoma (LADC), has been reported to be approximately 70-90%, as positive staining with p63 has been typically observed in 10-30% of LADC (1-6). Cocktails of p63 with complementary […]
TTF-1 (M), 2X is being discontinued. We will continue to offer these products until 06/30/16 or until current inventory is depleted, whichever occurs first. Biocare does offer TTF-1, catalog numbers CM087, PM087, IP087 as a substitute. Thyroid transcription factor-1 (TTF-1) is a member of the NKX2 family of homeodomain transcription factors. Studies have shown it […]
Thyroid transcription factor-1 (TTF-1) is a member of the NKX2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and lung. TTF-1 has been shown to be a sensitive (65-81%) and specific marker (94%) in the majority of primary lung adenocarcinomas. Studies have shown that TTF-1, used in combination […]
Tumor protein p63 antibody, also known as transformation-related protein 63 is a protein that in humans is encoded by the TP63 gene. Many studies have shown that p63 is a sensitive (90%) and fairly specific marker for squamous cell carcinoma and may be used in distinguishing poorly differentiated squamous cell carcinomas from adenocarcinomas. p63 has […]
Tumor protein p63 antibody, also known as transformation-related protein 63 is a protein that in humans is encoded by the TP63 gene. Many studies have shown that p63 is a sensitive (90%) and fairly specific marker for squamous cell carcinoma and may be used in distinguishing poorly differentiated lung squamous cell carcinomas (SqCC) from adenocarcinomas. […]
Glucose transporter 1, also known as GLUT-1 antibody or SLC2A1 is a protein in humans encoded by the SLC2A1 gene. GLUT-1 antibody facilitates the transport of glucose across the plasma membranes of mammalian cells. GLUT1 is responsible for the low-level of basal glucose uptake required to sustain respiration in all cells. Several glucose transporter protein […]
This is a monoclonal antibody to the A-subunit of human coagulation Factor XIII. Studies have shown it recognizes human Factor XIII Achain in both reduced and non-reduced forms. It does not react with human Factor XIII B-chain or human Factor XII. Factor XIII is a betaglobulin found in plasma and is composed of two subunits. […]
