MACH 3™

MACH 3 is a two-step, biotin-free detection system which provides excellent specificity, sensitivity and nuclear staining for mouse or rabbit primary antibodies. Biocare offers MACH 3 Detection Kits for either mouse or rabbit primary antibodies, labeled with either Horseradish Peroxidase (HRP) or Alkaline Phosphatase (AP). MACH 3 Features •A sensitivity-enhancing secondary reagent •Increased density of […]

Nuclear Decloaker, 10X

Nuclear Decloaker is a Tris buffer heat retrieval solution, pH 9.5. It is specially designed for nuclear antigens including ER, PR, Ki-67, p53, cyclin D1, TdT and TTF-1. Other antibodies that show improved staining include ALK1, ALKc, bcl-2, CA125, CD3 (M), CD15, CD30, CD31, CD79a, MART-1, Tyrosinase and Villin. Nuclear Decloaker can be used with […]

Vina Green Chromogen Kit staining colon cancer with Ki-67

Vina Green™ Chromogen Kit

Vina Green is a novel permanent chromogen that produces a green stain in the presence of horseradish peroxidase (HRP). The kit consists of liquid Vina Green chromogen and buffer that are stable, when mixed, for at least 4 hours at room temperature. Vina Green is clearly distinguishable from Warp Red and DAB on a single […]

Reactive atypia meets CIS in bladder: CD44 (blue), p53 (DAB) & CK20 (FR)

URO-3 Triple Stain

CD44 + p53 + CK20 can be used to differentiate urothelial reactive atypia from CIS (carcinoma in situ) in bladders. In normal urothelium, superficial umbrella cell layer shows reactivity for CK20 only, whereas CD44 staining is limited to the basal and parabasal urothelial cells and p53 nuclear staining is absent to focal. For urothelium with […]

(L) Bladder CIS & (R) Reactive atypia in bladder stained with Uro-2™

Uro-2 (CK20 + p53)

Uro-2 (CK20 + p53) is a primary antibody cocktail for the multiplex IHC identification of CK20 and p53 proteins in bladder. Studies have shown that in normal urothelium, the superficial umbrella cell layer shows reactivity for CK20 only; whereas, p53 nuclear staining is absent to focal. For urothelium with reactive atypia, particularly in cases with […]

Abstracts

A New and Innovative Antibody p16 INK4a [BC42]: An IHC Comparative Analysis with Clone [E6H4] NSH 2019 Download Rodent Multi-Species Multiplex Immunohistochemistry Using Digoxigenin and Polymer Detection Methods in Mouse Tissues AACR 2018 Download A Multiplex Immunohistochemistry Evaluation of Immune Checkpoint Receptors and Mismatch Repair Proteins in Colorectal Carcinoma AACR 2018 Download Sequential Multiplex Immunofluorescence […]

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