The 5p15.2 Green FISH Probe is a fluorescently labeled probe designed to hybridize to ~353 kb of the 5p15.2 region of chromosome 5. 5p15.2 Green probe (80 ng/µl) is provided in FISH Hybridization Buffer (FRR7311A) containing dextran sulfate and formamide.
The 5p15.2 Red FISH Probe is a fluorescently labeled probe designed to hybridize to ~353 kb of the 5p15.2 region of chromosome 5. 5p15.2 Red probe (40-100 ng/µl) is provided in FISH Hybridization Buffer (FRR7311A) containing dextran sulfate and formamide.
The TERC (3q26.2)/5p15.2/CCND1/Copy Control 6 CLEAR-VIEW FISH™ probe is directly labelled in CYMO-RED, CYMO-GREEN, CYMO-AQUA, and CYMO-ORANGE and is designed to detect copy number alterations of TERC(3q26.2), 5p15.2, CCND1, and Chromosome 6, respectively. A normal nucleus will show two red, two green, two aqua, and two orange signals.
The TERC (3q26.2)/5p15.2/Copy Control 7 CLEAR-VIEW FISH™ probe is directly labelled in CYMO-RED, CYMO-GREEN, and CYMO-AQUA and is designed to detect copy number alterations of TERC(3q26.2), 5p15.2, and Chromosome 7, respectively. A normal nucleus will show two red, two green, and two aqua signals.
The three color TERC (3q26.2)/5p15.2/CC 7 CLEAR-VIEW FISH™ direct labeled probe set is designed to detect copy numbers of 3q26.2 and 5p15.2 regions as well as enumeration of chromosome 7. The TERC (3q26) probe is ~618kb, located on chromosome 3q26.2 covering the TERC gene and is labeled in CYMO-ORANGE. The 5p15 probe is ~353kb, located […]
The MDM2 gene is located in the chromosomal region 12q15 and encodes for an E3 ubiquitin ligase which acts as a major negative regulator of the tumor suppressor p531. Due to amplification of the respective chromosomal region, MDM2 is overexpressed in many human tumors such as soft tissue sarcomas, osteosarcomas2, gliomas, NSCLC, gastric and breast […]
The CSF1R gene is consistently lost by partial deletions occurring in chromosome 5 in patients with Myelodysplastic syndrome (MDS)1. Specific deletion of the CSFS1R gene has been detected in as many as 40% of MDS patients. Studies have also shown that up to 58% of all breast carcinomas and 85% of invasive breast carcinomas express […]
p53 (RM), 2X is being discontinued. We will continue to offer these products until 06/30/16 or until current inventory is depleted, whichever occurs first. Biocare does offer p53, catalog numbers CME298, PME298, IP298 as a substitute. The tumor suppressor p53 plays a key role in regulating urothelial growth and genomic stability. Increased expression of p53 […]
CK5 (RM), 2X (Lung) is being discontinued. We will continue to offer these products until 06/30/16 or until current inventory is depleted, whichever occurs first. Biocare does offer Cytokeratin 5 (CK5), catalog numbers CME430, PME430 as a substitute. CK5 is a type II intermediate filament protein that is expressed in active basal layers of most […]
CK5/14, 3X (Breast) is being discontinued. We will continue to offer these products until 06/30/16 or until current inventory is depleted, whichever occurs first. Biocare does offer Cytokeratin 5/14 Cocktail, catalog numbers ACI3025, API3025 as a substitute. CK5/14, 3X antibody (Breast) [XM26 and LL002] is comprised of mouse monoclonal anti-CK5 and anti-CK14 antibodies. CK5 and […]
