CD31 recognizes a 100kDA glycoprotein in endothelial cells and 130kD in platelets. It reacts weakly with mantle zone B-cells, peripheral T-cells, and neutrophils.15 CD31 can detect vascular endothelium associated antigen and has been used as a marker for benign and malignant human vascular disorders, myeloid leukemia infiltrates and megakaryocytes in normal bone marrow.15-17 CD31 can […]
This antibody is optimized to work with Biocare Medical’s PromARK™ detection products for animal tissues. CD20 antibody (P) is a 33 kDa leukocyte surface antigen consisting of four transmembrane regions and cytoplasmic N- and C-termini. CD20 is expressed primarily on B-cells but has also been detected on both normal and neoplastic T-cells. This gene encodes […]
The causative bacterial agent of cat scratch disease has been identified as Bartonella henselae. In the past, complicated silver stains and/or PCR were used to identify and confirm this agent. This monoclonal Cat Scratch antibody aids to identify Bartonella henselae in formalin-fixed, paraffin-embedded (FFPE) tissues. Cross-reactivity tests were performed on 12 Bartonella henselae strains, 11 […]
Calretinin is a calcium binding protein that is related to calmodulin and calbindin-D28k and is found mainly in neuronal tissue. It is present in subsets of neurons throughout the brain and spinal cord, including sensory ganglia.15-19
Biotinylated Bromodeoxyuridine Antibody recognizes bromodeoxyuridine (BrdU), an analog to thymidine and can be incorporated into replicating DNA during the S-phase of the cell cycle. The BrdU antibody can be used for DNA labeling index, evaluation of DNA synthesis and cell proliferation studies. This antibody is biotinylated and thus eliminates the need for a biotinylated secondary […]
Arginase-1 (ARG-1) is a key enzyme of the urea cycle found in liver that catalyzes the conversion of L-arginine into L-ornithine and urea. ARG-1 is a highly specific and sensitive marker of benign and hepatocellular carcinoma (HCC) which is now a key target for the differential diagnosis of HCC from metastatic tumors to the liver.15-17 […]
AMACR (RM), 3X is being discontinued. We will continue to offer these products until 06/30/16 or until current inventory is depleted, whichever occurs first. Biocare does offer AMACR (RM) or AMACR (RM), 2X, catalog numbers APA3024, OAA3024 or APA3016 as a substitute. α-Methylacyl coenzyme A racemase (AMACR Antibody), also known as P504S, is a peroxisomal […]
α-Methylacyl coenzyme A racemase (AMACR Antibody), also known as P504S, is a peroxisomal and mitochondrial enzyme that plays a role in bile acid synthesis and β-oxidation of branched chain fatty acids. In immunohistochemistry, AMACR Antibody has been shown to be a specific marker of prostatic adenocarcinoma. Additionally, prostate glands involved in PIN have been found […]
α-Methylacyl coenzyme A racemase (AMACR antibody), also known as P504S, is a peroxisomal and mitochondrial enzyme that plays a role in bile acid synthesis and β-oxidation of branched chain fatty acids. In immunohistochemistry (IHC), AMACR antibody has been shown to be a specific marker of prostatic adenocarcinoma. Additionally, prostate glands involved in PIN have been […]
![(L) Anaplastic large cell lymphoma and (R) Lung adenocarcinoma stained with ALK antibody [5A4]](https://biocare.net/wp-content/uploads/3041.jpg)
ALK Antibody (p80) recognizes the formalin-resistant epitope of native anaplastic lymphoma kinase (ALK) protein. ALK Antibody specifically labels t(2;5)-positive cells giving strong cytoplasmic staining that is also associated with nuclear staining. Anaplastic large cell lymphoma (ALCL) is a heterogeneous group of diseases by morphology, immunophenotyping and clinical presentation that can be difficult to diagnose because […]
