(Left) Hyperplasia of the Usual Type (Right) Atypical Ductal Hyperplasia

CK5/14 + p63 + CK7/18 Multiplex IHC

IHC markers CK5, CK14, p63, CK7 and CK18 complement morphological evaluation of breast lesions, due to the differential expression of the luminal (CK7/18) vs. basal and myoepithelial markers (CK5/14, p63). Usual ductal hyperplasia is associated with positive basal cells markers, intermixed with positive luminal cells. Most atypical ductal hyperplasia and low grade ductal carcinoma in […]

Breast cancer stained with CK5 + p63

CK5 + p63

Cytokeratin 5 is a 58 kDa protein that is closely related to CK6. They share similar tissue distribution and are found in various proportions in many nonkeratinizing stratified squamous epithelia such as tongue mucosa, basal epithelia hair follicles, trachea, as well as basal cells in prostate glands and in mammary glands. CK5 is also expressed […]

Ventana and Biocare Medical sign p63 license agreement to aid in the differential diagnosis of benign and malignant prostate lesions

Ventana Medical Systems, Inc. (Ventana), a member of the Roche Group and Biocare Medical, LLC (Biocare) today announced that they have entered into a non-exclusive license agreement to allow Biocare access to certain patents and materials related to p63 diagnostics in the research and IVD field. In parallel, Biocare and AsymmetRx Medical, Inc. (AsymmetRx) have […]

Biocare Medical distribution rights and sampling program for IVD p63 antibody

Biocare Medical, LLC is pleased to announce a sampling program for p63 antibody for clinical and research laboratories. Biocare Medical is currently one of only two companies worldwide with rights to sell p63 antibodies for IVD testing purposes. Both predilute and concentrated antibodies are available. Biocare announced the favorable resolution of a challenge to its […]

p63 intellectual property suit settled in Biocare's favor

Biocare Medical , LLC of Concord, California is pleased to announce favorable resolution of a challenge to its non-exclusive worldwide license for p63 antibodies. The judgment makes Biocare one of only two companies that have rights to “make, use or sell” p63 antibodies, which make use of discoveries made at Harvard College. Following litigation launched […]

ONCORE Pro X – Protocols

Templates Download CK HMW + p63 + AMACR (RM) Download Ber-EP4 Download MOC-31 Download CD4 + CD8 Download  Mouse Amp AP Detection Download Mouse-on-Canine HRP-Polymer Download Mouse-on-Mouse AP-Polymer Download Mouse-on-Mouse HRP-Polymer Download Mouse-on-Rat HRP-Polymer Download Mouse-on-Rat AP-Polymer Download Ki-67 Rb – Vina Green Download Ki-67 Rb – Deep Space Black Download ONCORE Pro X Hematoxylin […]

ONCORE Pro – Protocols

  HPV Probes Download HPV 6 Probe Download HPV 11 Probe Download HPV 16 Probe Download HPV 18 Probe Download HPV 31 Probe Download HPV 51 Probe Download CISH DNA 1 Temp1 Download CISH DNA 2 Temp1 Download ONCORE Pro Warp Red Chromogen Kit Download ONCORE Pro Hematoxylin Download Molecular Probe / Templates Download ALK […]

Classification and Cocktails: Prostate Cocktail

Examining and diagnosing small prostate needle biopsies can be a difficult task. A final diagnosis of prostate carcinoma is based on histomorphological features.1 The difficulty with examining needle biopsy stems not only from the small amount of tissue available, but also from the fact that prostate biopsies often identify only a few malignant lesions and […]

Meeting the Mark: Desmoglein 3 + p40 + Napsin A

Lung cancer is the leading cause of cancer-related deaths in the United States and worldwide, with non-small cell lung cancer (NSCLC) accounting for 80% of lung cancers.1 NSCLC’s predominate subtypes are adenocarcinomas (ADC) and squamous cell carcinomas (SCC).1 Therapy of NSCLC depends on accurate histological classifications of these two subclassifications.1 Differentiating the two can be […]

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