Beta-Catenin Calponin c-erB-2/HER2 Cytokeratin 7 E-cadherin (Mouse) E-Cadherin Estrogen Receptor (ER) [6F11] Estrogen Receptor (ER) [SP1] Folate Receptor alpha IHC Assay Kit Gross Cystic Disease Fluid Protein-15 Ki-67 (M) Mammaglobin p53 p63 p40 (M) Phospho-Histone H3 Progesterone Receptor (PR) [PgR636] Progesterone Receptor (PR) [SP2] PTEN (Tumor Suppressor) Estrogen Receptor (ER) [6F11 + SP1] CK5/14 + […]
14
Apr
Apr
CK20, 2X is being discontinued. We will continue to offer these products until 06/30/16 or until current inventory is depleted, whichever occurs first. Biocare does offer Cytokeratin 20, catalog numbers CM062, PM062, IP062, OAI062 as a substitute. Cytokeratin 20 (CK20 antibody) is an intermediate filament protein that has been identified with expression primarily restricted to […]
17
Oct
Oct
Nuclear Decloaker is a Tris buffer heat retrieval solution, pH 9.5. It is specially designed for nuclear antigens including ER, PR, Ki-67, p53, cyclin D1, TdT and TTF-1. Other antibodies that show improved staining include ALK1, ALKc, bcl-2, CA125, CD3 (M), CD15, CD30, CD31, CD79a, MART-1, Tyrosinase and Villin. Nuclear Decloaker can be used with […]
03
Oct
Oct
CK5 and CK14 are high molecular weight cytokeratins expressed in a variety of normal and neoplastic epithelial tissues. p63, a homolog of the tumor suppressor p53, was detected in nuclei of the basal epithelium in normal prostate glands; however, it was not expressed in malignant tumors of the prostate. Expression of P504S protein is found […]
02
Oct
Oct
CD44 + p53 + CK20 can be used to differentiate urothelial reactive atypia from CIS (carcinoma in situ) in bladders. In normal urothelium, superficial umbrella cell layer shows reactivity for CK20 only, whereas CD44 staining is limited to the basal and parabasal urothelial cells and p53 nuclear staining is absent to focal. For urothelium with […]
30
Sep
Sep
Clone 1F8 recognizes a 105 kDa phosphoprotein, identified as retinoblastoma antibody (Rb) gene product. The epitope is localized between aa 703-772 of human Rb protein and shows no cross-reaction with p107 or p300. Studies have shown the retinoblastoma gene product to play a key role in cell cycle control. It has been identified as a […]
30
Sep
Sep
In normal epithelia, HMW Cytokeratins (CK5 and CK14) stain basal epithelia in the prostate gland.p63 is detected in prostate basal epithelial nuclei in normal prostate, however, is negative in malignant tumors of the prostate gland. Thus p63 is useful as a differential marker for benign and malignant tumors of the prostate gland and can be […]
25
Sep
Sep
p63, a homolog of the tumor suppressor p53, has been identified in proliferating basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium and prostate.1 p63 was detected in nuclei of the basal epithelium in normal prostate glands; however, it was not expressed in malignant tumors of the prostate.2 P504S, […]
25
Sep
Sep
PCNA [PC10], catalog number CM152B, is being discontinued. We will continue to offer this product until 06/30/16 or until current inventory is depleted, whichever occurs first. While no direct replacement is available, other cell proliferation markers we offer include Ki-67 and pHH3. Ki-67 is expressed in the nucleus during the whole cell cycle, except in […]
