Biocare’s PromARK™ series introduces Rabbit-on-Canine HRP-Polymer Detection. This detection is specially designed for using rabbit antibodies on canine and feline tissues and utilizes biotin-free horseradish peroxidase (HRP) polymer technology. The advantages of this polymer technology are increased sensitivity, reduction of IHC steps (no Avidin/Biotin block or Link/Probe), and minimal cross-reactivity to endogenous canine and feline […]
The Mouse-on-Canine AP-Polymer is designed using a one-step method for detecting mouse primary antibodies to form an antibody-enzyme complex. This complex is then visualized using an appropriate substrate/chromogen. In the one-step method a secondary antibody directly linked to the micro polymer is applied. Mouse-on-Canine AP-Polymer is provided ready-to-use.
The Mouse-on-Canine HRP-Polymer is designed using a one-step method for detecting mouse primary antibodies to form an antibody-enzyme complex. This complex is then visualized using an appropriate substrate/chromogen. In the one-step method a secondary antibody directly linked to the micro polymer is applied. Mouse-on-Canine HRP-Polymer is provided ready-to-use and is intended to be applied as […]
Fluoro Care Anti-Fade Mountant is an innovative, liquid-based, anti-fade mounting medium designed especially for the permanent preservation of fluorescent specimens. Fluoro Care is to be used with tissue sections stained with a multitude of fluorescent dyes. Fluoro Care is compatible with DyLightTM Fluors, Alexa Fluors®, fluorescein, rhodamine, Texas Red and stained specimens.
Fast Red is a widely used chromogen for immunohistochemical staining. When in the presence of alkaline phosphatase (AP) enzyme, Vulcan Fast Red produces a bright fuchsin-red precipitate that is insoluble in organic solvents and can be coverslipped with a permanent mounting media. This product is available in a stable two-component system, consisting of Vulcan Fast […]
Renal cell carcinoma antibody (RCC), also known as a gurnistical tumor, is a common form of adult kidney cancer localized to the tubule linings of the kidney. The prognosis for advanced RCC is poor due to its resistant to chemotherapy and radiation therapy. The RCC clone 66.4.C2 is a monoclonal antibody raised against a 200 […]
Pan Lymphoma Cocktail (LCA + CD20 + CD3 + CD43) are specific leukocyte markers used in the identification and assessment of lymphoid neoplasms. This combination of antibodies offers a marker for the identification of a variety of leukocytes. CD45 also known as leucocyte common antigen (LCA), is expressed on hematopoietic cell lines, but absent on […]
p120 Catenin, 2X is being discontinued. We will continue to offer these products until 06/30/16 or until current inventory is depleted, whichever occurs first. Biocare does offer p120 Catenin, catalog numbers ACI3008, API3008 as a substitute. p120 catenin plays a role in cytoskeletal anchoring in the adherens junctions between epithelial cells (1-2). In normal tissues, […]
p120 is a proliferation-associated nucleolar protein found in most human malignant tumors, but not in resting normal cells. The expression of p120 has been statistically correlated with the proliferation capacity in human lung cancer cells and could be a prognostic marker for resected Stage I lung adenocarcinoma.15-21
Diagnostic reproducibility of lobular vs. ductal lesions, based on histology alone, is less than optimal. The proper distinction between atypical lobular hyperplasia, lobular carcinoma in situ and low-grade ductal carcinoma in situ is critical for patient management. Studies have shown E-cadherin, a negative membrane marker for lobular neoplasia, is useful in the distinction of ductal […]
