06
Sep
Sep
Human CD10, also known as common acute lymphoblastic leukemia (CALLA), has been shown to react with TdT+ lymphoblastic leukemia, follicular germinal cell lymphoma, Burkitt’s lymphoma, and chronic myelocytic leukemia.15
06
Sep
Sep
Calponin a 34 kDa polypeptide, is a cytoskeleton-associated actin-binding protein that also interacts tropomyosin and calmodulin. Calponin antibody has been found to be useful as a marker for myoepithelial and basal lamina in differentiating microinvasive from in situ ductal carcinomas of the breast. Calponin antibody may also have applications in malignant myoepithelium and pleomorphic adenoma […]
06
Sep
Sep
Studies have shown that calcitonin antibody reacts with the human protein calcitonin and labels C-cells in normal thyroid. Calcitonin antibody has been reported to be particularly useful in differentiating medullary carcinoma from papillary and follicular thyroid cancer. Most medullary carcinomas are positive for calcitonin; conversely, most papillary and follicular types of thyroid cancer are usually […]
06
Sep
Sep
This antibody recognizes a protein of 185 kDa, identified as the second member (cerbB-2/HER-2) of the c-erbB family. This rabbit monoclonal antibody is directed against the cytoplasmic domain of the human c-erbB-2 protein. The c-erbB-2 is closely related in structure to the epidermal growth factor receptor.
05
Sep
Sep
c-erbB-2 antibody recognizes a protein of 185 kDa, identified as the second member (c-erbB-2/HER-2) of the c-erbB family. This mouse monoclonal antibody is directed against the cytoplasmic domain of the human c-erbB-2 protein. The c-erbB-2 protein is closely related in structure to the epidermal growth factor receptor and is over-expressed in a variety of carcinomas, […]
05
Sep
Sep
BOB-1 antibody is a B-lymphocyte-specific transcriptional co-activator for Oct-1 and Oct-2 transcription factors. BOB-1 and Oct-2 are useful for the B-lineage determination of CD20-plasmablastic or primary effusion subtypes of diffuse large B-cell lymphoma (DLBCL). Other studies have shown BOB-1, CD79a and Cyclin E are useful markers for discriminating classical Hodgkin’s lymphoma from primary mediastinal large […]
05
Sep
Sep
The 100/D5 antibody is highly specific to Bcl-2 antibody (alpha) and shows no cross-reactivity with Bcl-x or Bax protein. Bcl-2 (b-cell lymphoma #2) is a proto-oncogene located at 18q21.3. Expression of Bcl-2 alpha oncoprotein has been shown to inhibit apoptosis. In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 protein, whereas the […]
04
Sep
Sep
α-Methylacyl coenzyme A racemase (AMACR Antibody), also known as P504S, is a peroxisomal and mitochondrial enzyme that plays a role in bile acid synthesis and β-oxidation of branched chain fatty acids. In immunohistochemistry, AMACR Antibody has been shown to be a specific marker of prostatic adenocarcinoma. Additionally, prostate glands involved in PIN have been found […]
04
Sep
Sep
α-Methylacyl coenzyme A racemase (AMACR antibody), also known as P504S, is a peroxisomal and mitochondrial enzyme that plays a role in bile acid synthesis and β-oxidation of branched chain fatty acids. In immunohistochemistry (IHC), AMACR antibody has been shown to be a specific marker of prostatic adenocarcinoma. Additionally, prostate glands involved in PIN have been […]
