The G168-15 antibody recognizes human and mouse MLH-1 (80-85 kDa).1 MLH1 functions, along with MSH2, PMS2, and MSH6, as part of the DNA mismatch repair (MMR) pathway, are utilized by normal proliferating cells to repair mutations that may occur during DNA replication. It is thought that after MSH2 binds to a mismatched DNA duplex it […]