TBS Tween Buffer 20 10X is a buffered saline solution used as a washing reagent in immunohistochemical and in situ hybridization procedures. Tween 20 acts by permeabilizing cell membranes and favoring antibodies penetration in the tissue section facilitating the specific binding. In any immunohistochemical procedure, any antibody that is not bound to the antigen during […]
The 10X Cleaning Solution is intended for use in the NeoPATH Pro Cleaning Solution container. Cleaning Solution is a solution used for internal and external washes of the dispensing needle in the wash station. In addition, it is used in slide washes after antigen retrieval immunostaining and in thefinal slide wash after the detection step.
The NeoPATH Pro Universal Negative Control Serum is a cocktail of mouse IgG and rabbit IgG antibodies. It may be used in IHC assays where mouse and/or rabbit primary antibodies are used for antigen specific recognition and binding. The Negative Control Reagent is used in place of the primary antibody with a section of each […]
NeoPATH Pro Background Punisher is used to reduce background staining caused by non-specific protein binding that is often observed with immunohistochemistry. NeoPATH Pro Background Punisher is specifically formulated for pH stability and is sodium azide and thimerosal free. It can be used with automated or manual staining protocols.
The NeoPATH Pro Pepsin is designed as a digestive enzyme pretreatment of formalin-fixed, paraffin embedded (FFPE) tissues. Most immunohistochemistry (IHC) specimens are routinely fixed in formalin and, while formalin provides excellent preservation of morphology, it can greatly diminish the sensitivity to IHC. Formalin creates cross-links that alter protein biochemistry and can block antigenic sites. Antigen […]
The Dewax Solutions 1 (DS1) is a water-based solution for the removal of paraffin wax from FFPE tissue specimens, as part of an IHC staining procedure on the ONCORE Pro Automated Slide Stainer. Removal of paraffin wax must be performed prior to antigen retrieval and the application of reagents for immunostaining. The solution is provided […]
The MACH Infinity 10 is designed using a one-step method for detecting mouse and rabbit primary antibodies to form an antibody-enzyme complex. This complex is then visualized using an appropriate substrate/chromogen. In the one-step method a secondary antibody directly linked to the micropolymer is applied.
For use in higher throughput laboratories – The Rabbit HRP Detection is intended for use in Immunohistochemistry (IHC) staining protocols using a horseradish peroxidase (HRP) polymer one-step application method. This micro-polymer detection kit is designed for the detection of Rabbit IgG primary antibodies bound to target antigens in the formalin-fixed, paraffin-embedded (FFPE) tissues during the […]
For use in higher throughput laboratories – The Mouse Amp HRP Detection is intended for use in Immunohistochemistry (IHC) staining protocols using a horseradish peroxidase (HRP) polymer one-step application method. This micro-polymer detection kit is designed for the detection of mouse IgG and IgM primary antibodies bound to target antigens in the formalin-fixed, paraffin-embedded (FFPE) […]
This digoxigenin-labeled oligonucleotide probe recognizes human 28S ribosomal RNA within tissue sections.1,2 This probe can be used as a control when running specific RNA targeting probes. It should be used to assess RNA integrity in FFPE tissue sections. Weak or light staining in a test sample indicates that specifically targeted mRNA may be compromised.
