![Spleen stained with Glycophorin A [JC159] antibody](https://biocare.net/wp-content/uploads/3272.jpg)
Glycophorin A, which is the major membrane sialoglycoprotein of human red cells and their precursors, is a specific and early marker for the normal erythroid lineage.15 Glycophorin A is expressed at all stages of erythroid differentiation that includes both nucleated and non-nucleated stages of differentiation. Glycophorin A is a very important diagnostic marker of acute […]
![Tonsil stained with LMO2 [SP51] antibody.](https://biocare.net/wp-content/uploads/3262.jpg)
LMO2 is part of the LIM-only family of proteins which has four members (LMO1-4) that are implicated in a variety of cancers. LMO2 is linked to diffuse large B cell lymphoma (DLBCL) and prostate cancer (1). LMO2 protein is a nuclear marker, expressed in normal germinal-center (GC) B cells and in a subset of GC-derived […]
![Tonsil stained with CD137 [BLR051F] antibody](https://biocare.net/wp-content/uploads/3264.jpg)
CD137 (4-1BB), or tumor necrosis factor receptor superfamily member 9 (TNFRSF9), is a promising target for enhancing antitumor immune responses without the autoimmune side effects associated with immunotherapy approaches (1). CD137 signaling plays a significant role in multiple cells and regulates the activity of many immune cells. It can activate CD8+ T cells, induce cytokine […]
CK5 and CK14 are high molecular weight keratins expressed in the cytoplasm of basal cells and myoepithelium of breast tissue.15 p63 is a transcription factor present in the nuclei of myoepithelial cells.16 P504S is a peroxisomal and mitochondrial enzyme that plays a role in bile acid synthesis and β-oxidation of branched chain fatty acids.17
HPV Type 51 Probe is a digoxigenin-labeled DNA probe designed to hybridize to HPV Type 51 DNA sequences. HPV Type 51 Probe is provided in DNA Hybridization Buffer (BRI4036) containing dextran sulfate, nucleic acid carriers and formamide.
![Breast cancer stained with BCA-225 [Cu-18] antibody](https://biocare.net/wp-content/uploads/3241-1.jpg)
BCA-225 (Breast Cancer Antigen 225) is a 225 kD glycoprotein present in human breast carcinoma cells, as well as adenocarcinomas of the breast, kidney, ovary, and lung (1,2). Antibody clone Cu-18 was identified as specifically recognizing BCA-225 in breast carcinomas, in both the primary tumor and its metastatic derivatives (3,4). BCA-225 is considered to be […]
![Wilms' tumor stained with WT1 [rWT1/857] Antibody.](https://biocare.net/wp-content/uploads/3238_WT1_Wilms-tumor.jpg)
WT1 is a gene involved in the induction of Wilms’ tumor. In normal human tissues, WT1 mRNA has been observed in kidney, spleen and gonadal ridge mesoderm (1). WT1 expression has also been observed in sertoli cells of testes and in granulosa cells of the ovary. In tumors, WT1 has been demonstrated in Wilms’ tumors […]
Copy Control 15 Green FISH Probe is designed to hybridize to human α-satellite DNA sequences located at the centromere region of chromosome 15. The clinical interpretation of any positive or negative hybridization events should be complemented by the use of appropriate controls and other diagnostic tests where appropriate. Evaluation should be carried out within the […]
P504S, also known as α-Methylacyl coenzyme A racemase (AMACR), is a peroxisomal and mitochondrial enzyme that plays a role in bile acid synthesis and β-oxidation of branched chain fatty acids (1). AMACR was initially identified from a cDNA library as a gene that is over-expressed in human prostate cancer; with little or no expression in […]
CK5 and CK14 are high molecular weight cytokeratins expressed in a variety of normal and neoplastic epithelial tissues (1). In prostate tissue, mRNA for CK5 and CK14 has been detected in the basal cells of normal glands and prostatic intraepithelial neoplasia (PIN), a precursor lesion to prostatic adenocarcinoma; however, expression of CK5 or CK14 was […]
