p63 has been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with reported sensitivities of 80-100% (1-6). Specificity for lung SqCC, versus lung adenocarcinoma (LADC), has been reported to be approximately 70-90%, as positive staining with p63 has been typically observed in 10-30% of LADC (1-6). Cocktails of p63 with complementary […]
CK5/14, 3X (Breast) is being discontinued. We will continue to offer these products until 06/30/16 or until current inventory is depleted, whichever occurs first. Biocare does offer Cytokeratin 5/14 Cocktail, catalog numbers ACI3025, API3025 as a substitute. CK5/14, 3X antibody (Breast) [XM26 and LL002] is comprised of mouse monoclonal anti-CK5 and anti-CK14 antibodies. CK5 and […]
p63, a homolog of the tumor suppressor p53, has been identified in proliferating basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium and prostate.1 p63 was detected in nuclei of the basal epithelium in normal prostate glands; however, it was not expressed in malignant tumors of the prostate.2 P504S, […]
![Prostate cancer stained with p63 [4a4] antibody, 2X](https://biocare.net/wp-content/uploads/th.jpg)
p53 homologue p63 encodes for different isotypes able to either transactivate p53 reporter genes (TAp63) or act as p53-dominant-negatives. Studies have shown that p63 [4a4] antibody detection by IHC has clinical utility in the evaluation of lung, prostate, cervical and other types of cancer in formalin fixed, paraffin-embedded (FFPE) human tissues. A cocktail of p63 […]
p63, 3X (Prostate) is being discontinued. We will continue to offer these products until 06/30/16 or until current inventory is depleted, whichever occurs first. Biocare does offer p63, catalog numbers CM163, PM163, IP163, VP163, OAI163 as a substitute. p63, a homolog of the tumor suppressor p53, has been identified in proliferating basal cells in the […]
p63, 3X (Breast) is being discontinued. We will continue to offer these products until 06/30/16 or until current inventory is depleted, whichever occurs first. Biocare does offer p63, catalog numbers CM163, PM163, IP163, VP163, OAI163 as a substitute. p63, 3X (Breast) [4A4] is comprised of a mouse monoclonal anti-p63 antibody. p63 is a transcription factor […]
Tumor protein p63 antibody, also known as transformation-related protein 63 is a protein that in humans is encoded by the TP63 gene. Many studies have shown that p63 is a sensitive (90%) and fairly specific marker for squamous cell carcinoma and may be used in distinguishing poorly differentiated squamous cell carcinomas from adenocarcinomas. p63 has […]
The p63 + CK5 Multiplex IHC stain has been especially designed for squamous cell carcinomas, particularly those derived in lung cancer. p63, a homolog of the tumor suppressor p53, has been identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate.15 CK5 is a 58 […]
Tumor protein p63 antibody, also known as transformation-related protein 63 is a protein that in humans is encoded by the TP63 gene. Many studies have shown that p63 is a sensitive (90%) and fairly specific marker for squamous cell carcinoma and may be used in distinguishing poorly differentiated lung squamous cell carcinomas (SqCC) from adenocarcinomas. […]
p63, a homolog of the tumor suppressor p53, has been identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate.15 p63 was detected in nuclei of the basal epithelium in normal prostate glands; however, it was not expressed in malignant tumors of the prostate.16 As […]
