CD22 [BLCAM/1796] is a type 1 integral membrane glycoprotein with molecular weight of 130 to 140 kDa. It is expressed in both the cytoplasm and cell membrane of B-lymphocytes. CD22 antigen appears early in B-cell lymphocyte differentiation at approximately the same stage as the CD19 antigen (1). CD22 may be a useful marker for phenotyping […]
Approximately 12,000 men and women in the United States are diagnosed with gallbladder cancer annually, leading to an annual estimated 4,000 deaths.1 Gallbladder and other biliary cancers are comparatively rare in the United States, with about 0.7% of new cancer cases classified as gallbladder, contributing approximately 0.6% of cancer deaths yearly.1 Worldwide, gallbladder and other […]
PIK3CA mutations have been discovered in many cancers including, colon, breast, endometrial, brain, skin, gastric, lung and thyroid1,2. Extensive studies have led researchers to believe that PIK3CA is one of the most commonly mutated oncogenes in human cancers3. These amplification events can be readily identified using appropriate FISH probes.
Immunocare TBS Wash Buffer (sodium azide and thimerasol free) works well for manual and automated immunohistochemistry applications as well as other laboratory procedures requiring a high quality TBS buffer with superior pH stability. The buffer contains surfactant and allows for reagents to spread more uniformly across tissue sections on slides. It has been specifically formulated […]
Immunocare PBS Wash Buffer (sodium azide free) works well for manual and automated immunohistochemistry applications as well as other laboratory procedures requiring a high quality PBS buffer with superior pH stability. The PBS contains surfactant and allows for reagents to spread more uniformly across tissue section on slides. It can also be used on an […]
CAT Hematoxylin sections in pretreated formalin-fixed, paraffin-embedded tissue cellular preparations in is used to visualize cellular nuclei in tissue sections and immunohistochemistry. CAT Hematoxylin is a Mayer’s Hematoxylin (Lillie modification) histological staining reagent for use in the histologic demonstration of nuclear staining. It is also used in special-staining procedures as a counterstain for nuclear demonstration. […]
Pronase (Streptomyces griseus) is a commonly used digestive enzyme. In formalin-fixed paraffin-embedded tissues, certain antibody protocols require enzyme pretreatment for proper immunohistochemical staining. CAREZYME III is an aggressive enzyme and can be used at room temperature or at 37°C. Certain antibodies such as EGFR require this type of aggressive enzyme digestion. This product is provided […]
Pepsin is a commonly used digestive enzyme. For formalin-fixed paraffin-embedded tissues, certain antibody protocols require enzyme pretreatment for proper immuno-histochemical staining. This product is provided as a single-component, ready-to-use solution. It can also be used on an automated staining system.
Trypsin is a commonly used digestive enzyme. In formalin-fixed paraffin-embedded tissues, certain antibody protocols required enzyme pretreatment for proper immunohistochemical staining. This product is provided as a two component, ready-to-use solution, and can be used at different concentrations.
Biocare’s PromARK™ series introduces Rabbit-on-Canine AP-Polymer Detection. This detection is specially designed for using rabbit antibodies on canine and feline tissues and utilizes biotin-free alkaline phosphatase (AP) polymer technology. The advantages of this polymer technology are increased sensitivity, reduction of IHC steps (no Avidin/Biotin block or Link/Probe), and minimal cross-reactivity to endogenous canine and feline […]
