p120 Catenin, 2X is being discontinued. We will continue to offer these products until 06/30/16 or until current inventory is depleted, whichever occurs first. Biocare does offer p120 Catenin, catalog numbers ACI3008, API3008 as a substitute. p120 catenin plays a role in cytoskeletal anchoring in the adherens junctions between epithelial cells (1-2). In normal tissues, […]
p120 is a proliferation-associated nucleolar protein found in most human malignant tumors, but not in resting normal cells. The expression of p120 has been statistically correlated with the proliferation capacity in human lung cancer cells and could be a prognostic marker for resected Stage I lung adenocarcinoma.15-21
Diagnostic reproducibility of lobular vs. ductal lesions, based on histology alone, is less than optimal. The proper distinction between atypical lobular hyperplasia, lobular carcinoma in situ and low-grade ductal carcinoma in situ is critical for patient management. Studies have shown E-cadherin, a negative membrane marker for lobular neoplasia, is useful in the distinction of ductal […]
Making the distinction between ductal carcinoma in situ (DCIS) and lobular carcinoma (LCIS) can be difficult in some situations. The proper distinction between atypical lobular hyperplasia, lobular carcinoma in situ and low-grade ductal carcinoma in situ is critical for patient management.¹ While histology is the first line of distinction, subsequent immunostains are highly useful. Studies […]
Beta-Catenin Calponin c-erB-2/HER2 Cytokeratin 7 E-cadherin (Mouse) E-Cadherin Estrogen Receptor (ER) [6F11] Estrogen Receptor (ER) [SP1] Folate Receptor alpha IHC Assay Kit Gross Cystic Disease Fluid Protein-15 Ki-67 (M) Mammaglobin p53 p63 p40 (M) Phospho-Histone H3 Progesterone Receptor (PR) [PgR636] Progesterone Receptor (PR) [SP2] PTEN (Tumor Suppressor) Estrogen Receptor (ER) [6F11 + SP1] CK5/14 + […]
Concord, CA, June 10, 2013 – Biocare Medical is proud to announce the availability of a new line of Supernova antibodies. Supernovas contain a higher antibody concentration than standard predilutes, providing versatility to a client’s current test menu. At Biocare, we aim to enable the client to consider all options and determine the most optimal […]
E-Cadherin is a transmembrane glycoprotein that plays a key role in cellcell adhesion in epithelial tissues (1-2). The adherens junction between epithelial cells is comprised of extracellular domains of E-Cadherin from adjacent cells, which interact through a molecular zipper motif. In normal tissues, immunostaining of E-Cadherin is localized to the membrane of epithelial cells, consistent […]
Galectin-3 shows strong diffuse cytoplasmic staining in most cases of papillary thyroid carcinoma (PTC), including the classical and follicular variant (1). Follicular carcinomas with minimal and extensive invasion may also express galectin-3 (2). Most poorly differentiated thyroid cancers demonstrate galectin-3 protein expression while it is not expressed in anaplastic thyroid cancers (3,4). Medullary thyroid carcinomas […]
Lung cancers are the third most diagnosed cancer in the United States, with about 13.5% of new cancer cases classified as lung, contributing 27.2% of cancer deaths yearly. As of 2011, there were approximately 402,000 people living with lung cancer in the United States. Those diagnosed with lung cancer have a 5 year survival rates […]
