Thyroid transcription factor-1 (TTF-1) is a 38 kDa member of the NKX2 family of homeodomain transcription factors. TTF-1 is mostly detected in primary lung adenocarcinomas and small cell carcinomas.1 No cytoplasmic staining in lung cancers has been observed with clone SPT24.2
TTF-1 has been the premier marker for lung adenocarcinoma. Another promising marker, Napsin A, is expressed in type II pneumocytes and in adenocarcinomas of the lung (1). Studies have shown Napsin A to be more sensitive and specific than TTF-1 in lung adenocarcinomas, and virtually negative in all squamous carcinomas. In other studies, comparing TTF-1 […]
Thyroid transcription factor-1 (TTF-1) is a member of the NKX2 family of homeodomain transcription factors. Studies have shown that TTF-1 is expressed in epithelial cells of the thyroid gland and lung. TTF-1 has been shown to be a sensitive (62-80%) and specific marker (89-95%) in the majority of primary lung adenocarcinomas (ADC) (1-7). When combined […]
TTF-1 (M), 2X is being discontinued. We will continue to offer these products until 06/30/16 or until current inventory is depleted, whichever occurs first. Biocare does offer TTF-1, catalog numbers CM087, PM087, IP087 as a substitute. Thyroid transcription factor-1 (TTF-1) is a member of the NKX2 family of homeodomain transcription factors. Studies have shown it […]
TTF-1 is a member of the NKX2 family of homeodomain transcription factors found in epithelial cells of the thyroid gland and lung. TTF-1 has been shown to stain approximately 65-70% of cases of lung adenocarcinomas (ADC), with a small number of cases of lung squamous cell carcinoma (SCC) also positive for TTF-1 (1-4). Napsin A […]
TTF-1 has been the premier marker for lung adenocarcinoma. A new and promising marker, Napsin A, is expressed in type II pneumocytes and in adenocarcinomas of the lung (2). Studies have shown Napsin A to be more sensitive and specific than TTF-1 in lung adenocarcinomas and virtually negative in all squamous carcinomas. In other studies […]
Thyroid transcription factor-1 (TTF-1) is a member of the NKX2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and lung. TTF-1 has been shown to be a sensitive (65-81%) and specific marker (94%) in the majority of primary lung adenocarcinomas. Studies have shown that TTF-1, used in combination […]
Thyroid transcription factor-1 (TTF-1) is a member of the NKX2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate and adrenal glands are not reactive. TTF-1 is detected in primary lung adenocarcinomas […]
HPV Probes Download HPV 6 Probe Download HPV 11 Probe Download HPV 16 Probe Download HPV 18 Probe Download HPV 31 Probe Download HPV 51 Probe Download CISH DNA 1 Temp1 Download CISH DNA 2 Temp1 Download ONCORE Pro Warp Red Chromogen Kit Download ONCORE Pro Hematoxylin Download Molecular Probe / Templates Download ALK […]
