Smooth Muscle-Myosin Heavy Chain (SM-MHC) is a cytoplasmic structural protein that is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early and is specific for smooth muscle development.15
Immunoglobulin lambda light chain mRNA may be detected in normal and neoplastic B-cells in human lymphoid tissue (1-3). Lambda Light Chain Probe is a digoxigenin-conjugated DNA oligonucleotide designed to bind human lambda light chain mRNA.
Immunoglobulin kappa light chain mRNA may be detected in normal and neoplastic B-cells in human lymphoid tissue (1-3). Kappa Light Chain Probe is a digoxigenin-conjugated DNA oligonucleotide designed to bind human kappa light chain mRNA.
Immunoglobulin kappa light chain mRNA may be detected in normal and neoplastic B-cells in human lymphoid tissue (1-3). Kappa Light Chain Probe is a digoxigenin-conjugated DNA oligonucleotide designed to bind human kappa light chain mRNA.
The Lambda Light Chain [N10/2] antibody is a mouse monoclonal antibody developed for the detection of lambda light chains of human immunoglobulins. Immunoglobulin light chains exist in two classes: kappa and lambda. In healthy individuals, the kappa to lambda ratio is approximately 2:1.19-20 Detection of light chain restriction can aid in the diagnosis of lymphoid […]
This antibody recognizes kappa light chains of human immunoglobulins, which may be useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas (1-5). The most common feature of these malignancies is the restricted expression of a single light chain class. The normal human kappa/lambda ratio is approximately 2:1. The presence of clear cut light […]
Immunoglobulin lambda light chain mRNA may be detected in normal and neoplastic B-cells in human lymphoid tissue (1-3). Lambda Light Chain Probe is a digoxigenin-conjugated DNA oligonucleotide designed to bind human lambda light chain mRNA.
Smoothelin [R4A] is a mouse monoclonal antibody directed to the cytoskeletal component of smooth muscle cells (SMC) known as smoothelin. Smoothelin is exclusively expressed in fully differentiated (contractile) SMCs. Smoothelin antibody has been reported to be a useful tool in monitoring SMC differentiation; and may aid in the distinction of terminally differentiated smooth muscle cells, […]
Smooth Muscle Actin (SMA) antibody recognizes the alpha-smooth muscle isoform of actin. According to studies, it shows no cross-reactivity with actin from fibroblasts (beta- and gamma-cytoplasmic), striated muscle (alpha-sarcomeric) and myocardium (alpha-myocardial). A synthetic peptide corresponding to N-terminus of human alpha-actin was used as immunogen. SMA stains smooth muscle cells in vessel walls, gut wall […]
This antibody recognizes the alpha-smooth muscle isoform of actin. It shows no cross-reaction with actin from fibroblasts (beta- and gamma-cytoplasmic), striated muscle (alpha-sarcomeric), and myocardium (alpha-myocardial). Its epitope is composed of the acetyl group and the first 4 amino acids on the Nterminal end of the peptidic chain of alpha-smooth actin.15
