MART-1 recognizes a protein of 18 kDa, identified at MART-1 (Melanoma Antigen Recognized by T cells 1). MART-1 is a useful addition to melanoma panels as it is specific for melanocytic lesions (1- 3). Studies have shown that MART-1 is more sensitive than HMB45 when labeling metastatic melanomas (3). Tyrosinase is a key enzyme involved […]
MART-1 recognizes an 18 kDa protein (Melanoma Antigen Recognized by T cells 1) and is specific for melanocytic lesions, making it a valuable component of melanoma panels.15-17 MART-1 has been shown to be more sensitive than HMB45 for labeling metastatic melanomas. Tyrosinase, a key enzyme in early melanin biosynthesis, is more sensitive than HMB45 and […]
The SOX11 (M) [SOX11-C1] antibody is a mouse monoclonal antibody developed for the detection of SOX11 (SRY-box transcription factor 11), a member of the SOX family of transcription factors involved in embryonic development and cellular differentiation.15 SOX11 is strongly expressed in most cases of mantle cell lymphoma (MCL), including those that are cyclin D1-negative, making […]
SOX10 Antibody The SOX10 protein is widely expressed in normal human tissues including melanocytes and breast tissue. It is also an important marker in malignant tumors such as melanoma, breast carcinoma, gliomas and benign tumors such as schwannomas. SOX10 antibody has been shown to be expressed in 97-100% of desmoplastic and spindle cell melanomas and […]
Lung cancers are the third most diagnosed cancer in the United States, with about 13.5% of new cancer cases classified as lung, contributing 27.2% of cancer deaths yearly. As of 2011, there were approximately 402,000 people living with lung cancer in the United States. Those diagnosed with lung cancer have a 5 year survival rates […]
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Biocare Medical takes great pride in our promise of “Fighting Cancer, One Slide at a Time.” Our focus in the fight against cancer is realized through our high-quality immunohistochemistry (IHC) and in situ hybridization (ISH) reagents and instrumentation. Specifically, our sensitive and specific antibodies, molecular probes, and detection chemistries support early and accurate classification of […]
