For kidney, ovarian and thyroid cancers, PAX8 has been shown to be a useful marker which can identify both primary and metastatic tumors of these types. PAX8 nuclear expression is easily interpreted and diagnosed in the presence of non-specific background staining. Unfortunately, the currently available commercial anti-PAX8 (P) polyclonal antibodies have the disadvantage of cross-reactivity […]
Biocare Medical, LLC has been awarded United States Patent No. US 8,852,592 for the anti-PAX8 mouse monoclonal antibody, clone [BC12]. This mouse monoclonal PAX8 antibody [BC12] has been designed to target a restricted epitope and exhibits higher specificity and provides sharper staining than the PAX8 rabbit polyclonal antibody. This clone was developed in-house and is […]
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Sep
Sep
PAX8 Antibody PAX8 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins which contain a paired box domain, an octapeptide, and a paired-type homeodomain. This family plays critical roles during fetal development and cancer growth. PAX8 is involved in kidney cell differentiation, thyroid development, […]
25
Sep
Sep
PAX8 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins which contain a paired box domain, an octapeptide, and a paired-type homeodomain. This family plays critical roles during fetal development and cancer growth. PAX8 is involved in kidney cell differentiation, thyroid development, or thyroid […]
Biocare Medical is proud to announce the launch of a mouse monoclonal PAX8 antibody. Unlike current existing PAX8 polyclonals, the PAX8 mouse clone [BC12] has been designed for specific epitope targeting. The monoclonal PAX8 does not stain B-cells, cells of pancreatic origin or neuroendocrine cells of the stomach or colon. This antibody also has lower […]
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What Tissues Are You Working With?
19
Dec
Dec
Biocare Medical takes great pride in our promise of “Fighting Cancer, One Slide at a Time.” Our focus in the fight against cancer is realized through our high-quality immunohistochemistry (IHC) and in situ hybridization (ISH) reagents and instrumentation. Specifically, our sensitive and specific antibodies, molecular probes, and detection chemistries support early and accurate classification of […]
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