The NeoPATH Pro Pepsin is designed as a digestive enzyme pretreatment of formalin-fixed, paraffin embedded (FFPE) tissues. Most immunohistochemistry (IHC) specimens are routinely fixed in formalin and, while formalin provides excellent preservation of morphology, it can greatly diminish the sensitivity to IHC. Formalin creates cross-links that alter protein biochemistry and can block antigenic sites. Antigen […]
Probe Enhancer (RNA) is an ancillary reagent that is used as a diluent for RNA targeting probes in an ISH procedure. Probe Enhancer (RNA) facilitates spreading of probes and reduces drying of RNA during hybridization reactions. Effective hybridization may facilitate enhanced staining and reduce artifacts.
ONCORE Pro Hematoxylin is water-based and is specially formulated for counterstaining on Biocare’s ONCORE Pro Automated Stainer. ONCORE Pro Hematoxylin stains nuclei sky-blue and provides high contrast staining for chromogenic staining procedures.
Fast Red is a well-established chromogen used in IHC staining protocols that in the presence of an alkaline phosphatase (AP) enzyme, produces a bright fuchsin-red precipitate that is insoluble in organic solvents and can be coverslipped with a permanent mounting media. ONCORE Pro Warp Red Chromogen Kit contains two solutions: Warp Red Chromogen and the […]
The Rabbit Amp AP Detection is designed using a one-step method for detecting Rabbit primary antibodies to form an antibody-enzyme complex. This complex is then visualized using an appropriate substrate/chromogen. In the one-step method a secondary antibody directly linked to the micropolymer is applied. Rabbit Amp AP Detection is provided ready-to-use and is intended to […]
Immunoglobulin lambda light chain mRNA may be detected in normal and neoplastic B-cells in human lymphoid tissue (1-3). Lambda Light Chain Probe is a digoxigenin-conjugated DNA oligonucleotide designed to bind human lambda light chain mRNA.
The Epstein – Barr virus is a member of the gamma-herpes viruses (HHV-4). Epstein-Barr Encoded (EBER) Probe is a digoxigenin-conjugated DNA oligonucleotide designed to bind EBER-1 and EBER-2 mRNA sequences that may be expressed in latently infected cells.1
Immunoglobulin kappa light chain mRNA may be detected in normal and neoplastic B-cells in human lymphoid tissue (1-3). Kappa Light Chain Probe is a digoxigenin-conjugated DNA oligonucleotide designed to bind human kappa light chain mRNA.
Antigen Retrieval 3 (AR3) is capable of partially breaking the covalent bonds of formalin-fixed tissue, as part of an ISH staining procedure on the ONCORE Pro Automated Slide Stainer. Pretreatment of FFPE tissues with Antigen Retrieval 3 (AR3) can increase staining intensity. Probe Enhancer (RNA) is an ancillary hybridization reagent that promotes spreading and reduces […]
CytoFISH products are now manufactured and sold by Empire Genomics, a Biocare Medical company. ONCORE Pro CytoFISH Kit contains reagents used in the pretreatment of cytological specimens to enhance probe accessibility to nucleic acid targets as well as a post-hybridization buffer used to eliminate nonspecific binding of the probe. Cytological specimens with FISH protocols usually […]
