The product Master Polymer Plus Detection System (Peroxidase) (Incl. DAB Chromogen) is an immunohistochemistry developer kit. It is designed for the detection of monoclonal and polyclonal primary antibodies obtained in mice and rabbits. The kit is designed for laboratory use by automated immunohistochemistry on paraffin-embedded tissue in neoplasms and in all other clinicopathological and physiological […]
For use in higher throughput laboratories –The Rabbit Amp AP Detection is intended for use in Immunohistochemistry (IHC) staining protocols using an alkaline phosphatase (AP) polymer one-step application method. This micro-polymer detection kit is designed for the detection of rabbit primary antibodies bound to target antigens in the formalin-fixed, paraffin-embedded (FFPE) tissues during the IHC […]
For use in higher throughput laboratories –The Mouse Amp AP Detection is intended for use in Immunohistochemistry (IHC) staining protocols using an alkaline phosphatase (AP) polymer one-step application method. This micro-polymer detection kit is designed for the detection of mouse IgG and IgM primary antibodies bound to target antigens in the formalin-fixed, paraffin-embedded (FFPE) tissues […]
Chromogenic in situ hybridization (ISH) permits the visual identification of specific mRNA or DNA nucleic acid sequences in tissues. Following application of the probe, the presence of a target nucleic acid is visualized by the sequential application of a secondary reagent that binds the digoxigenin labeled probe, followed by a tertiary enzyme-antibody conjugate, and a […]
Insulinoma-associated protein 1 (INSM1), a zinc-finger transcription factor, is a key regulator of neuroendocrine differentiation during development, and has recently emerged as a reliable immunostaining marker with a nuclear staining pattern for the identification of neuroendocrine and neuroepithelial neoplasms.15,16 Several studies have demonstrated nuclear INSM1 expression in multiple neuroendocrine tumor types, including small cell carcinomas […]
![Tonsil stained with CD54 [E3Q9N] antibody.](https://biocare.net/wp-content/uploads/3296.jpg)
CD54, also known as Intercellular adhesion molecule 1 (ICAM1) is a 90 kDa glycosylated transmembrane protein of the immunoglobulin superfamily. CD54 plays an important role in immunological synapse formation, T-cell activation, leukocyte migration, and numerous cellular immune responses.15 While some studies have shown that CD54 promotes tumor metastasis by regulating various signaling pathways in some […]
![Spleen stained with HLA-B [BC43] antibody](https://biocare.net/wp-content/uploads/3289.jpg)
HLA-B is a highly polymorphic protein encoding gene for the major histocompatibility class I (MHC-I) complex.15 MHC class I molecules are expressed on the cell surface, binding and presenting antigenic peptides to CD8+ T lymphocytes to mediate immune responses against intracellular pathogens and cancers.16 Want to Learn More About HLA-B [BC43] Antibody? Download Our Complimentary […]
![Kaposi sarcoma stained with HHV-8 [13B10] antibody](https://biocare.net/wp-content/uploads/3290.jpg)
Human herpesvirus 8 (HHV-8) also known as Kaposi sarcoma-associated herpesvirus (KSHV), encodes a latent nuclear antigen which is the product of the viral gene ORF73.1 The protein is expressed predominantly during viral latency and appears to play a role in viral integration into the host genome.1 HHV-8 is associated with Kaposi’s sarcoma, primary effusion lymphoma, […]
