The p16 + Ki-67 multiplex has proven an important biomarker for high-risk HPV1,2. This novel multiplex cocktail of p16 INK4a [BC42] and Ki-67 [SP6] may aid in the identification of cells co-expressing markers for both tumor suppression and cell proliferation, an indicator of cellcycle deregulation3. Using H&E diagnosis, cervical intraepithelial neoplasia (CIN) lesions were classified […]
Jul
p16 INK4a is a tumor suppressor protein involved in the pathogenesis of a variety of malignancies. p16 INK4a is a 16.5 kDa protein expressed in the nucleoplasm of proliferating cells, functioning as an inhibitor of CDK4. Recent analyses of the p16 INK4a gene revealed homozygous deletions, nonsense, missense, or frameshift mutations in several human cancers […]
Apr
The Ki-67 nuclear antigen is associated with cell proliferation and found throughout the cell cycle; though not in G0 phase (1,2). The assessment of Ki-67 proliferation in breast cancers has shown the Ki-67 labelling index is an important predictor of survival (3). Cytokeratin (CK) 7 is expressed in epithelial cells of the ovary, lung and […]
Feb
The Ki-67 nuclear antigen is associated with cell proliferation and found throughout the cell cycle; though not in G0 phase (1,2). The assessment of Ki-67 proliferation in breast cancers has shown the Ki-67 labelling index is an important predictor of survival (3). Microscopic evaluation of mitotic figures on H&E is a routine procedure in the […]
Nov
The Ki-67 nuclear antigen is associated with cell proliferation. It is found throughout the cell cycle that includes the G1, S, G2, and M phases; but not the (G0) phase.15-17 Want to Learn More About Glucagon Antibody? Download Our Complimentary White Paper!
Sep
Pan Melanoma Antibody + Ki-67 serves as a tool to identify the proliferation rate of melanocytic lesions in cases in which melanocytes are sparse; there are dense lymphocytic infiltrates; and melanocytes are admixed with fibroblasts. In general, a higher proliferative fraction is seen in melanoma than in melanocytic nevi. There are many types of nevi, […]
Sep
Ki-67 + Caspase-3 can provide information on cell death vs. cell proliferation in the same tissue section. The Ki-67 nuclear antigen is associated with cell proliferation and is used to grade proliferation rates of tumors. Ki-67 is found throughout the cell cycle that includes the G1, S, G2, and M phases; but not the G0 […]
Sep
The Ki-67 nuclear antigen is associated with cell proliferation. It is found throughout the cell cycle in the G1, S, G2, and M phases; but not the (GO) phase. It is used to grade proliferation rates of tumors. The high affinity and/or binding capacity of rabbit antibodies provide superior staining results and less chance for […]
Templates Download CK HMW + p63 + AMACR (RM) Download Ber-EP4 Download MOC-31 Download CD4 + CD8 Download Mouse Amp AP Detection Download Mouse-on-Canine HRP-Polymer Download Mouse-on-Mouse AP-Polymer Download Mouse-on-Mouse HRP-Polymer Download Mouse-on-Rat HRP-Polymer Download Mouse-on-Rat AP-Polymer Download Ki-67 Rb – Vina Green Download Ki-67 Rb – Deep Space Black Download ONCORE Pro X Hematoxylin […]
