CD8 [C8/1779R] is a rabbit monoclonal antibody that is intended for laboratory use in the qualitative identification of CD8a protein by immunohistochemistry (IHC) in formalin-fixed paraffin-embedded (FFPE) human tissues. The clinical interpretation of any staining or its absence should be complemented by morphological studies using proper controls and should be evaluated within the context of […]
CD4 is expressed in a T-cell subset (helper/inducer) and is found in approximately 80% of thymocytes and in 45% of peripheral blood lymphocytes. CD4 is expressed in the majority of T-cell lymphomas including mycosis fungoides, a common form of cutaneous T-cell lymphoma (1). CD8 has been shown to be an important marker in the analysis […]
The CD8 antibody reacts with the 32 kDa CD8 protein. CD8 stains cells with cytotoxic activity, including cortical thymocytes, cytotoxic/suppressor T-cells and a subset of natural killer cells. CD4 and CD8 positive and negative staining are indicative of T-cell neoplasms (1-2). CD4 and CD8 may also be used to differentiate between mycosis fungoides and cutaneous […]
CD8 is a cell surface glycoprotein member of the immunoglobulin superfamily. CD8 consists of two chains, alpha and beta, which are expressed as a disulphide-linked alpha/beta heterodimer or as an alpha/alpha homodimer on a subset of T-cells, thymocytes and NK cells.15 The majority of CD8+ T cells express CD8 as alpha/beta heterodimer. CD8 functions as […]
![Spleen stained with HLA-B [BC43] antibody](https://biocare.net/wp-content/uploads/3289.jpg)
HLA-B is a highly polymorphic protein encoding gene for the major histocompatibility class I (MHC-I) complex.15 MHC class I molecules are expressed on the cell surface, binding and presenting antigenic peptides to CD8+ T lymphocytes to mediate immune responses against intracellular pathogens and cancers.16 Want to Learn More About HLA-B [BC43] Antibody? Download Our Complimentary […]
Templates Download CK HMW + p63 + AMACR (RM) Download Ber-EP4 Download MOC-31 Download CD4 + CD8 Download Mouse Amp AP Detection Download Mouse-on-Canine HRP-Polymer Download Mouse-on-Mouse AP-Polymer Download Mouse-on-Mouse HRP-Polymer Download Mouse-on-Rat HRP-Polymer Download Mouse-on-Rat AP-Polymer Download Ki-67 Rb – Vina Green Download Ki-67 Rb – Deep Space Black Download ONCORE Pro X Hematoxylin […]
HPV Probes Download HPV 6 Probe Download HPV 11 Probe Download HPV 16 Probe Download HPV 18 Probe Download HPV 31 Probe Download HPV 51 Probe Download CISH DNA 1 Temp1 Download CISH DNA 2 Temp1 Download ONCORE Pro Warp Red Chromogen Kit Download ONCORE Pro Hematoxylin Download Molecular Probe / Templates Download ALK […]
![Appendix stained with IFNG [IFNG/3996R] antibody](https://biocare.net/wp-content/uploads/3266.jpg)
Interferon-gamma (IFNG) is a cytokine secreted predominantly by activated lymphocytes such as CD4 T helper type 1 (Th1) cells and CD8 cytotoxic T cells, natural killer cells, B cells, and antigen-presenting cells. IFNG expression is induced by mitogens and cytokines (1). The downstream target genes of IFNG signaling pathway regulate several biological functions, including cell […]
![Tonsil stained with CD137 [BLR051F] antibody](https://biocare.net/wp-content/uploads/3264.jpg)
CD137 (4-1BB), or tumor necrosis factor receptor superfamily member 9 (TNFRSF9), is a promising target for enhancing antitumor immune responses without the autoimmune side effects associated with immunotherapy approaches (1). CD137 signaling plays a significant role in multiple cells and regulates the activity of many immune cells. It can activate CD8+ T cells, induce cytokine […]
