CD71 (transferrin receptor), a cell surface proliferation marker, is involved in the cellular uptake of iron.15,17 CD71 has been shown to exhibit strong membranous and cytoplasmic staining in all erythroid precursors of normal and dyspeptic bone marrow biopsies.15,16
CD79a antibody is an intracellular component of the signal transduction pathway of the B-cell Receptor, appearing at pre-B-cell stage and persisting until the plasma cell stage. Studies have shown that CD79a is found in a majority of acute leukemia of precursor-B-cell-type as well as B-cell neoplasms, B-cell lymphomas and some myelomas. It is not present […]
The CD7 molecule is a membrane-bound glycoprotein of 40 kDa and is the earliest T-cell specific antigen to be expressed in lymphocytes. CD7 is expressed in the majority of thymocytes, peripheral blood T-cells and natural killer cells. Used in combination with CD4, CD7 is useful for differentiating mycosis fungoides and memory T-cells.15,16
What Tissues Are You Working With?
Biocare Medical takes great pride in our promise of “Fighting Cancer, One Slide at a Time.” Our focus in the fight against cancer is realized through our high-quality immunohistochemistry (IHC) and in situ hybridization (ISH) reagents and instrumentation. Specifically, our sensitive and specific antibodies, molecular probes, and detection chemistries support early and accurate classification of […]
CD4, a member of the immunoglobulin superfamily, is a transmembrane glycoprotein, expressed on mature thymocytes, T-helper cells, the majority of mature peripheral T cells, and a subset of suppressor or cytotoxic T cells (1). In lymphoid tissue, CD4 expression can be found in the paracortical T zone. CD4+ T cells are also seen scattered in […]
CD4 is expressed in a T-cell subset (helper/inducer) and is found in approximately 80% of thymocytes and in 45% of peripheral blood lymphocytes. CD4 is expressed in the majority of T-cell lymphomas including mycosis fungoides, a common form of cutaneous T-cell lymphoma (1). CD8 has been shown to be an important marker in the analysis […]
CD4 is a transmembrane glycoprotein, expressed on normal thymocytes, T-helper cells, the majority of mature peripheral T cells, and a subset of suppressor or cytotoxic T cells (1). Like many cell surface receptors/markers, CD4 is a member of the immunoglobulin superfamily. CD4 is expressed in the majority of T-cell lymphomas, including mycosis fungoides (2). CD4 […]
