The CD68 antigen is a 110 kDa highly glycosylated transmembrane protein which is mainly located in lysosomes. Studies have shown the antibody stains macrophages in many human tissues including Kupffer’s cells and macrophages in the red pulp of the spleen, in lung alveoli, in lamina propria of the gut, and in the bone marrow. 15 […]
The Biocare CD33 antibody detects CD33 (Siglec-3), a 67 kDa glycosylated transmembrane receptor expressed on myeloid-specific cells.15, 16 Historically, CD33 was primarily used for flow cytometry; more recently, a paraffin embedded tissue–compatible CD33 antibody has been developed. CD33 is useful for phenotyping acute myelogenous leukemias, with immunohistochemical (IHC) analysis providing results equivalent to flow cytometry.15, […]
