CD23 is a 45 kDa glycoprotein that acts as a receptor for IgE. It is expressed by interleukin-4 activated B-lymphocytes, by activated macrophages, and by a proportion of follicular dentritic cells. CD23 has been shown to be useful for the differentiation of small lymphocytic lymphomas and mantle cell lymphoma.15
CD10, also known as common acute lymphoblastic leukemia (CALLA), has been shown to react with B and T lymphoblastic leukemia/lymphoma, follicular lymphoma, Burkitt’s lymphoma, and diffuse large B-cell lymphoma (1-3). CD10 has also been a very important marker in a panel, including CD20, CD5, CD23, cyclin D1, SOX11, BCL6 among others, to differentiate between small […]
CD11c (also known as Leu-M5 or Integrin alpha X) [5D11] is a member of the leukointegrin family. CD11c is a cell surface adhesion receptor and is predominantly expressed in tissue macrophages, dendritic cells, monocytes, NK cells and granulocytes. CD11c has been shown to be both sensitive and specific for hairy cell leukemia (HCL) (1). CD11c […]
EDTA Decloaker is a heat retrieval solution, pH 8.4-8.7. Recommended for use with antibodies with low antigen expression (cyclin D1, CD1a, CD3, CD4, CD8, CD23, bcl-6, CD61, CD79a and TdT). EDTA Decloaker is a potent agent for epitope retrieval and tissues may be 5-10 times more sensitive to immunohistochemical staining. EDTA Decloaker can be used […]
This rabbit monoclonal antibody recognizes a protein of 36 kDa, identified as Cyclin D1 (also known as Bcl-1 or PRAD-1). Cyclin D1 is a regulatory subunit of certain protein kinases thought to advance the G1 phase of the cell cycle.15 Cyclin D1 used in tandem with CD5, CD10 and CD23 is the most reliable immunohistochemical […]
This rabbit monoclonal antibody recognizes a protein of 36 kDa, identified as Cyclin D1 (also known as Bcl-1 or PRAD-1). Cyclin D1 is a regulatory subunit of certain protein kinases thought to advance the G1 phase of the cell cycle.15 Cyclin D1 used in tandem with CD5, CD10 and CD23 is a reliable immunohistochemical marker […]
