CD10, also known as common acute lymphoblastic leukemia (CALLA), has been shown to react with B and T lymphoblastic leukemia/lymphoma, follicular lymphoma, Burkitt’s lymphoma, and diffuse large B-cell lymphoma (1-3). CD10 has also been a very important marker in a panel, including CD20, CD5, CD23, cyclin D1, SOX11, BCL6 among others, to differentiate between small […]
The Biocare CD103 [EP206] antibody detects the integrin subunit CD103, a cell surface antigen characteristically expressed in hairy cell leukemia (HCL), a Bcell lymphoproliferative disorder.15,17 CD103 [EP206] has demonstrated reactivity in formalin-fixed paraffinembedded (FFPE) tissue, eliminating the need for flow cytometry or frozen section IHC and making it a valuable component of an IHC panel […]
Human CD10, also known as common acute lymphoblastic leukemia (CALLA), has been shown to react with TdT+ lymphoblastic leukemia, follicular germinal cell lymphoma, Burkitt’s lymphoma, and chronic myelocytic leukemia.15
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How to Utilize a Denaturing Solution Step to Eliminate Cross-Reactivity Double or multiple antigen labeling in immunohistochemistry (IHC) classically relies on the existence of primary antibodies raised in different species or of different IgG isotypes to ensure the specific labeling with the secondary detection systems.1 With an abundance of mouse primary antibodies and increase of […]
What Tissues Are You Working With?
Biocare Medical takes great pride in our promise of “Fighting Cancer, One Slide at a Time.” Our focus in the fight against cancer is realized through our high-quality immunohistochemistry (IHC) and in situ hybridization (ISH) reagents and instrumentation. Specifically, our sensitive and specific antibodies, molecular probes, and detection chemistries support early and accurate classification of […]
Deciphering the Immune System in Small Intestine: Immune Related Antibodies and Multiplex Strategies for Inflammatory Bowel Disease Multiplex Cocktails for Immunotherapy Targets: PD-L1 with Tumor Specific Transcription Factors Immunohistochemical Double and Triple Stain Strategies with CD8, CD103, FOXP3, PD-1 and CK8/18 in Colon Adenocarcinoma: Quantitation, Prognosis and Immunotherapy
Immunotherapy, also called biologic therapy or biotherapy, is a type of treatment designed to boost the body’s immune system to fight diseases, including cancer. It stimulates and awakens one’s own defense system to improve, target, or restore immune system function. In the last few decades, immunotherapy has become an important part of treating some types […]
