MACH 2™

MACH 2 Detection is a one-step / one-solution, biotin-free detection system which combines superior work flow and sensitivity for mouse and rabbit primary antibodies.

MACH 2 detection consists of a single reagent applied after the primary antibody. MACH 2 is ideal for use with prediluted antibodies or concentrates with equal success. MACH 2 may be used for 7-step multiplex stains with certain antibodies.

MACH 2 increases staining specificity compared to conventional dextran backbone polymer. MACH 2 is available in anti-mouse, anti-rabbit, and ‘universal’ (anti-mouse & anti-rabbit) formulations, labeled with either Horseradish Peroxidase (HRP) or Alkaline Phosphatase (AP).

  • Increase specificity 3-4 fold in nuclear staining & 2 fold in cytoplasmic/cell surface staining
  • Superior to dextran backbone polymers
Compare MACH 2 (L) with conventional 3-step avidin-biotin / ABC system (R)


MACH 2 gives a clean and sharp signal

MACH 2 gives a clean and sharp signal


Endogenous biotin background is detected in tissue around the artery

Endogenous biotin background is detected in tissue around the artery


Ordering Information

MACH 2 Universal HRP-Polymer Detection

$231.00$2,184.00 Select options

MACH 2 Mouse HRP-Polymer Detection

$163.00$8,472.00 Select options

MACH 2 Mouse AP-Polymer

$206.00$1,257.00 Select options

MACH 2 Rabbit HRP-Polymer

$171.00$8,896.00 Select options

MACH 2 Rabbit AP-Polymer

$215.00$1,319.00 Select options