Surfactant apoprotein-A

Double stain of Surfactant Apoprotein-A (red) and TTF-1 (brown)

The expression of Surfactant-apoprotein-A (SP-A) by the tumor cells has been a helpful diagnostic tool for the identification of primary carcinomas of the lung. SP-A is expressed in pneumocytes II of lung tissue and in a portion of non-small cell lung carcinomas. Immunohistochemically detected SP-A using the monoclonal antibody 32E12 in conjunction with thyroid transcription factor-1 (or other lung carcinoma identifying antibodies) may be a useful means of diagnosing lung malignancies of unknown primary origin. SP-A does not cross-react with thyroid.

Specifications  
Intended Use
Source
Species Reactivity ,
Clone
Isotype ,
Antigen
Cellular Localization
Positive Control
Normal Tissue
Abnormal Tissue
Ordering Information Catalog Number Volume
Concentrate CM 275 A, C
Predilute PM 275 AA
intelliPATH™ N/A N/A
VP Echelon N/A N/A
A / AK = 0.1 ml B / BK = 0.5 ml C / CK = 1.0 ml G5 = 5.0 ml AA = 6.0 ml H / G25 = 25 ml L = 100 ml
Data Sheets
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