CDX2 + CK7
CDX2 is a homeobox gene that encodes an intestine-specific transcription factor. It is expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is a superior marker compared to CK20 and can be substituted in a panel of antibodies.
| Specifications |
|
| Intended Use |
IVD |
| Source |
Mouse Monoclonal, Rabbit Monoclonal |
| Species Reactivity |
Human, Others not tested |
| Clone |
CDX2-88 + BC1 |
| Isotype |
IgG, IgG1 |
| Antigen |
CDX2-88 + BC1 |
| Cellular Localization |
Cytoplasmic, Nuclear |
| Positive Control |
Breast Cancer, Colon, Lung, Ovarian |
| Normal Tissue |
Breast, Colon |
| Abnormal Tissue |
Breast, Colon, Lung |
| Ordering Information |
Catalog Number |
Volume |
| Concentrate |
N/A |
N/A |
| Predilute |
PM 367DS |
AA, H, L |
| intelliPATH™ |
IP 367 DS |
G10 |
| VP Echelon |
N/A |
N/A |
| A / AK = 0.1 ml |
B / BK = 0.5 ml |
C / CK = 1.0 ml |
G5 = 5.0 ml |
AA = 6.0 ml |
H / G25 = 25 ml |
L = 100 ml |
