Uroplakin II + Uroplakin III

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SKU: API 3094 Categories: , , ,

Uroplakin II [BC21] and Uroplakin III [BC17] are highly specific antibodies that may be useful in identifying tumors of urothelial origin. With the exception of bladder and ureter, staining was highly specific in various normal and neoplastic tissues in an in-house study. Both antibodies exhibited increased staining sensitivity when compared to Uroplakin III [AU1] in cases of urothelial carcinoma of the bladder. Uroplakin II + Uroplakin III antibody may be a specific and sensitive antibody cocktail for urothelial carcinoma and in discriminating bladder cancer from renal and prostate carcinomas. PATENT PENDING.

Intended Use

IVD

Format

Predilute

Source

Mouse Monoclonal

Clone

BC21, BC17, Biocare Clone

Isotype

IgG1

Antigen

Residues 36-50, Uroplakin III

Localization

Cytoplasmic, Membrane

Species Reactivity

Human

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moderately sensitive immunohistochemical marker for primary and metastatic
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