L26 + CD3

$338.00

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L26 + CD3 antibodies allow B-cell and T-cell lymphomas to be identified on the same slide. L26 (CD20) reacts with the majority of B-cells present in peripheral blood and lymphoid tissues. In normal lymphoid tissue, L26 marks B-cells in germinal centers, particularly immunoblasts and rarely marks T-cells. This antibody has been shown to be a reliable pan B-cell marker. The rabbit monoclonal CD3 reacts with the intracytoplasmic portion of the CD3 antigen expressed by T-cells. CD3 stains human T-cells in both the cortex and medulla of the thymus and in peripheral lymphoid tissues.

Intended Use

IVD

Species Reactivity

Human, Others Not Tested

Source

Mouse Monoclonal, Rabbit Monoclonal

Clone

L26 + SP7

Isotype

IgG2a + Rabbit IgG

Antigen

L26: B-cells , CD3: T-cells

Localization

L26: cytoplasmic (red), CD3: cytoplasmic (brown)

Positive Control

Tonsil

1. Nguyen DT, et al. Hematopathol Mol Hematol. 1996; 10(3):135-50.
2. Chadburn A, Knowles DM. Am J Clin Pathol. 1994 Sep; 102(3):284-91.
3. Davey FR, et al. Am J Pathol. 1987 Oct; 129(1):54-63.

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