Herpes Simplex Virus 2 (2X)

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This antibody reacts with Herpes Simplex Virus (HSV) 2. HSV 2 antibody identifies major viral envelope glycoproteins and core proteins that can be found in the cytoplasm and/or nucleus. HSV can infect both the peripheral and central nervous system. Studies have shown that HSV Type 2 infects the genitals and anus. Studies have shown this antibody does not cross-react with cytomegalovirus, Epstein-Barr virus, or varicella zoster virus and is compatible with formalin fixation; however, prolonged fixation can be detrimental to HSV staining.

Intended Use

ASR

Clone

N/A

Isotype

N/A

1. Yoshida K, et al. Ascitic fluid due to type II herpes simplex virus infection: Report of a case with immunohistochemical confirmation. Diagn Cytopathol. 2012 Jan 27. doi: 10.1002 /dc.21775.
2. Martin JR, et al. Type-specific identification of herpes simplex and varicella-zoster virus antigen in autopsy tissues. Hum Pathol. 1991 Jan;22(1):75-80.
3. Tomita T, Chiga M, Lenahan M, Balachandran N. Identification of herpes simplex virus infection by immunoperoxidase and in situ hybridization methods. Virchows Arch A Pathol Anat Histopathol. 1991;419(2):99-105.
4. Center for Disease Control Manual. Guide: Safety Management, NO. CDC-22, Atlanta, GA. April 30, 1976 “Decontamination of Laboratory Sink Drains to Remove Azide Salts.”
5. Clinical and Laboratory Standards Institute (CLSI). Protection of Laboratory Workers from Occupationally Acquired Infections; Approved guideline-Third Edition CLSI document M29-A3 Wayne, PA 2005.

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