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This antibody reacts with Herpes Simplex Virus (HSV) 2. HSV 2 antibody identifies major viral envelope glycoproteins and core proteins that can be found in the cytoplasm and/or nucleus. HSV can infect both the peripheral and central nervous system. Studies have shown that HSV Type 2 infects the genitals and anus. Studies have shown this antibody does not cross-react with cytomegalovirus, Epstein-Barr virus, or varicella zoster virus and is compatible with formalin fixation; however, prolonged fixation can be detrimental to HSV staining.
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