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Heat shock proteins (HSPs) are an important part of the cell’s machinery for protein folding and also help to protect cells from stress. HSPs are expressed in tumor cell proliferation, differentiation, invasion and metastasis. In addition to improving overall protein integrity, Heat Shock Protein 70 antibody (HSP70) directly inhibits apoptosis and has been shown to be involved in a protective role against thermal stress and cytotoxic drugs. Recently, HSP70 has been reported as a prognostic marker in multiple cancer types.
HSP70 from HeLa cells
Nuclear and cytoplasmic
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