Follicle Stimulating Hormone (FSH)

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Follicle Stimulating Hormone antibody (FSH) is a hormone found in humans and other animals. It is synthesized and secreted by gonadotrophs of the anterior pituitary gland. FSH is involved in the maturation of ovarian follicles and estrogen secretion in females. In males, FSH stimulates the secretion of testosterone. Studies have shown that FSH may be a useful marker in the study of pituitary disease, classification of pituitary tumors and in the differential diagnosis of primary and metastatic tumors of the pituitary.

Intended Use

IVD

Species Reactivity

Human

Source

Mouse Monoclonal

Clone

FSH03

Isotype

IgG1 /kappa

Antigen

FSH-ß

Localization

Cytoplasmic

Positive Control

Anterior pituitary

1. Nicholas S. Immunoperoxidase staining of primate pituitaries with antibodies against the ß subunits of human pituitary glycoprotein hormones. J Histochem Cytochem 28:837-43, 1981.
2. Osamura RY et al. Immunohistochemical studies of human FSH producing pituitary adenomas. Virchows Arch A Pathol Anat Histopathol 413(1):61-8. 1988.
3. Trouillas J. et al. Normal and tumorous human gonadotropic cells. Ann Endocrinol 51(2): 54-64.1990.
4. Center for Disease Control Manual. Guide: Safety Management, NO. CDC-22, Atlanta, GA. April 30, 1976 “Decontamination of Laboratory Sink Drains to Remove Azide Salts.”
5. National Committee for Clinical Laboratory Standards (NCCLS). Protection of laboratory workers from infectious diseases transmitted by blood and tissue; proposed guideline. Villanova, PA 1991;7(9). Order code M29-P.

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