Epidermal Growth Factor Receptor

Clear
SKU: 063 Categories: ,

Epidermal Growth Factor Receptor antibody [H11] reacts with a 170kDa (wild type) and 145kDa (vIII variant) protein, identified as the first member of type I family of growth factor receptors (initially identified as EGR-Receptor). The EGFR antibody H11 clone shows no cross reactivity with c-erbB-2, cerbB-3 or c-erbB-4. Various studies have observed and reported over-expression of EGFR in tumors of breast (25%), brain, bladder, lung, gastric, esophagus, cervix, ovary and endometrium.

Intended Use

IVD

Species Reactivity

Human

Source

Mouse Monoclonal

Clone

H11

Isotype

IgG1

Antigen

EGFR

Localization

Cell membrane and some cytoplasmic

Positive Control

Squamous cell carcinoma or skin

1. Koo JS, et al. Neoplasma. 2011; 58(1):27-34.
2. Brustmann H, et al. Int J Gynecol Pathol. 2011 Jan; 30(1):76-83.
3. Vranic S, et al. Hum Pathol. 2010 Nov; 41(11):1617-23.

Reviews


There are no reviews yet.

Be the first to review “Epidermal Growth Factor Receptor”