Cytokeratin 5/6

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Studies have shown Cytokeratin 5/6 antibody reacts with human epidermis and non-keratinizing epithelium. It has also been shown to react with cytokeratin 6, weakly with cytokeratin 4, and does not react with cytokeratins 1, 7, 8, 10, 13, 14, 18 and 19. CK5/6 has been shown to express in the vast majority of squamous cell carcinoma, basal cell carcinomas, thymomas, salivary gland tumors, and mesothelioma. It rarely reacts with pulmonary adenocarcinomas.

Intended Use

IVD

Species Reactivity

Human

Source

Mouse Monoclonal

Clone

CK5/6.007

Isotype

IgG1

Antigen

CK5/6

Localization

Cytoplasmic

Positive Control

Prostate or skin

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Regulatory Notice: Biocare’s IVD-labeled products comply with US-FDA and European IVDD regulation. Other regions may have additional requirements for such labeling, please contact your local distributor.

1. Ordonez NG. Am J Surg Pathol. 1998 Oct; 22(10):1215-21.
2. Chu P, Weiss LM. Mod Pathol. 2002 Jan; 15(1):6-10.
3. Aquiar FN, et al. Clinics (Sao Paulo). 2013 May; 68(5):638-43.

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