Cytokeratin 5

Clear
SKU: 234 Categories: , ,

Cytokeratin 5 Antibody is a 58 kDa protein that is closely related to CK6. ELISA testing has shown the XM26 clone was positive for CK5 and negative for the CK6 protein. CK5 is in many non-keratinizing stratified squamous epithelia such as tongue mucosa, basal epithelia hair follicles and trachea. It is also expressed in prostate gland basal cells, mammary gland myoepithelial cells and most epithelial and biphasic mesotheliomas. According to various studies, CK5 is expressed in large cell carcinomas and pulmonary squamous cell carcinomas. The sensitivity of CK5 for identifying basal-like tumors in breast was 97% compared with 59% for CK5/6.

Intended Use

IVD

Species Reactivity

Human

Source

Mouse Monoclonal

Clone

XM26

Isotype

IgG1 /kappa

Antigen

CK5

Localization

Cytoplasmic

Positive Control

Normal prostate

Antibody Download
Download Oncore Protocol
Oncore™ Protocol Installation Instructions        Download

1. Bocker W, et al. Lab Invest. 2002 Jun; 82(6):737-46.
2. Miettinen M, Sarlomo-Rikala M. Am J Surg Pathol. 2003 Feb; 27(2):150-8.
3. Bhargava R, et al. Am J Clin Pathol. 2008 Nov; 130(5):724-30.
4. Brunnstrom H, et al. Am J Clin Pathol. 2013 Jul; 140(1):37-46.

Reviews


There are no reviews yet.

Be the first to review “Cytokeratin 5”