CD30

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CD30 antibody [Ki-1] is expressed in mononuclear Hodgkin’s and multinucleated Reed-Sternberg cells in Hodgkin’s disease, in tumor cells of a majority of anaplastic large cell lymphomas, in a varying proportion of activated T and B cells and by embryonal carcinomas. It aids in distinguishing large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells, or from anaplastic carcinomas. Compared to other CD30 mouse antibodies, [Ber-H2] has shown stronger labeling intensity and higher percentage of positively labeled cells.

Intended Use

IVD

Species Reactivity

Human

Clone

Ber-H2

Isotype

IgG1/kappa

Antigen

CD30

Localization

Cell Membrane

Positive Control

Hodgkin’s or anaplastic large cell lymphoma

1. Tilly H, et al. Blood. 1997 Nov; 90(9):3727-34.
2. Filippa DA, et al. Blood. 1996 Apr; 87(7):2905-17.
3. Clavio M, et al. Leuk Lymphoma. 1996 Jul; 22(3-4):319-27.
4. Pallesen G, Hamilton-Dutoit SJ. Am J Pathol. 1988 Dec; 133(3):446-50.

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